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Propafenone Poisoning of a Female Adolescent After a Suicide Attempt

Propafenone is an antiarrhythmic agent for the management of ventricular and supraventricular tachycardia and atrial fibrillation. Propafenone poisoning is rare but may be life-threatening due to drug-induced arrhythmias. Electrocardiographic changes in PR, QRS, and QT intervals have been recorded....

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Autores principales: Keramari, Stergiani, Poutoglidis, Alexandros, Poutoglidou, Frideriki, Kaiafa, Georgia, Keramaris, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380293/
https://www.ncbi.nlm.nih.gov/pubmed/34434676
http://dx.doi.org/10.7759/cureus.16576
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author Keramari, Stergiani
Poutoglidis, Alexandros
Poutoglidou, Frideriki
Kaiafa, Georgia
Keramaris, Michael
author_facet Keramari, Stergiani
Poutoglidis, Alexandros
Poutoglidou, Frideriki
Kaiafa, Georgia
Keramaris, Michael
author_sort Keramari, Stergiani
collection PubMed
description Propafenone is an antiarrhythmic agent for the management of ventricular and supraventricular tachycardia and atrial fibrillation. Propafenone poisoning is rare but may be life-threatening due to drug-induced arrhythmias. Electrocardiographic changes in PR, QRS, and QT intervals have been recorded. We present a case of a 15-year-old female adolescent who developed arrhythmias and convulsions due to propafenone intoxication, in an attempt to commit suicide. The outcome of the case was a full recovery from the arrhythmias and the seizures. The aim of this article is to highlight the possibility of a lethal intoxication by a common antiarrhythmic drug. Our case aims to present our therapeutic strategy that relies mainly on close monitoring of patients and cardiac output support.
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spelling pubmed-83802932021-08-24 Propafenone Poisoning of a Female Adolescent After a Suicide Attempt Keramari, Stergiani Poutoglidis, Alexandros Poutoglidou, Frideriki Kaiafa, Georgia Keramaris, Michael Cureus Cardiology Propafenone is an antiarrhythmic agent for the management of ventricular and supraventricular tachycardia and atrial fibrillation. Propafenone poisoning is rare but may be life-threatening due to drug-induced arrhythmias. Electrocardiographic changes in PR, QRS, and QT intervals have been recorded. We present a case of a 15-year-old female adolescent who developed arrhythmias and convulsions due to propafenone intoxication, in an attempt to commit suicide. The outcome of the case was a full recovery from the arrhythmias and the seizures. The aim of this article is to highlight the possibility of a lethal intoxication by a common antiarrhythmic drug. Our case aims to present our therapeutic strategy that relies mainly on close monitoring of patients and cardiac output support. Cureus 2021-07-23 /pmc/articles/PMC8380293/ /pubmed/34434676 http://dx.doi.org/10.7759/cureus.16576 Text en Copyright © 2021, Keramari et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Keramari, Stergiani
Poutoglidis, Alexandros
Poutoglidou, Frideriki
Kaiafa, Georgia
Keramaris, Michael
Propafenone Poisoning of a Female Adolescent After a Suicide Attempt
title Propafenone Poisoning of a Female Adolescent After a Suicide Attempt
title_full Propafenone Poisoning of a Female Adolescent After a Suicide Attempt
title_fullStr Propafenone Poisoning of a Female Adolescent After a Suicide Attempt
title_full_unstemmed Propafenone Poisoning of a Female Adolescent After a Suicide Attempt
title_short Propafenone Poisoning of a Female Adolescent After a Suicide Attempt
title_sort propafenone poisoning of a female adolescent after a suicide attempt
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380293/
https://www.ncbi.nlm.nih.gov/pubmed/34434676
http://dx.doi.org/10.7759/cureus.16576
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