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The m6A methyltransferase METTL3 controls epithelial-mesenchymal transition, migration and invasion of breast cancer through the MALAT1/miR-26b/HMGA2 axis

BACKGROUND: Previous studies have revealed the key functions of N6-methyladenosine (m6A) modification in breast cancer (BC). MALAT1 as a highly m6A modified lncRNA associated with cancer development and metastasis, but the functional relevance of m6A methyltransferase and MALAT1 in BC is still unkno...

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Detalles Bibliográficos
Autores principales:	Zhao, Chengpeng, Ling, Xiaoling, Xia, Yunxia, Yan, Bingxue, Guan, Quanlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380348/ https://www.ncbi.nlm.nih.gov/pubmed/34419065 http://dx.doi.org/10.1186/s12935-021-02113-5

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