Anti-AQP4 autoantibodies promote ATP release from astrocytes and induce mechanical pain in rats

BACKGROUND: Intractable neuropathic pain is a common symptom of neuromyelitis optica spectrum disorder (NMOSD). However, the underlying mechanism of NMOSD pain remains to be elucidated. In this study, we focused on ATP, which is one of the damage-associated molecular patterns, and also a well-recogn...

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Detalles Bibliográficos
Autores principales: Ishikura, Teruyuki, Kinoshita, Makoto, Shimizu, Mikito, Yasumizu, Yoshiaki, Motooka, Daisuke, Okuzaki, Daisuke, Yamashita, Kazuya, Murata, Hisashi, Beppu, Shohei, Koda, Toru, Tada, Satoru, Shiraishi, Naoyuki, Sugiyama, Yasuko, Miyamoto, Katsuichi, Kusunoki, Susumu, Sugimoto, Tomoyuki, Kumanogoh, Atsushi, Okuno, Tatsusada, Mochizuki, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380350/
https://www.ncbi.nlm.nih.gov/pubmed/34419102
http://dx.doi.org/10.1186/s12974-021-02232-w

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