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B1 lymphocytes develop independently of Notch signaling during mouse embryonic development

B1 lymphocytes are a small but unique component of the innate immune-like cells. However, their ontogenic origin is still a matter of debate. Although it is widely accepted that B1 cells originate early in fetal life, whether or not they arise from hematopoietic stem cells (HSCs) is still unclear. I...

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Detalles Bibliográficos
Autores principales: Azevedo Portilho, Nathalia, Scarfò, Rebecca, Bertesago, Elisa, Ismailoglu, Ismail, Kyba, Michael, Kobayashi, Michihiro, Ditadi, Andrea, Yoshimoto, Momoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380455/
https://www.ncbi.nlm.nih.gov/pubmed/34370006
http://dx.doi.org/10.1242/dev.199373