Fis1 ablation in the male germline disrupts mitochondrial morphology and mitophagy, and arrests spermatid maturation

Male germline development involves choreographed changes to mitochondrial number, morphology and organization. Mitochondrial reorganization during spermatogenesis was recently shown to require mitochondrial fusion and fission. Mitophagy, the autophagic degradation of mitochondria, is another mechani...

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Detalles Bibliográficos
Autores principales: Varuzhanyan, Grigor, Ladinsky, Mark S., Yamashita, Shun-ichi, Abe, Manabu, Sakimura, Kenji, Kanki, Tomotake, Chan, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380467/
https://www.ncbi.nlm.nih.gov/pubmed/34355730
http://dx.doi.org/10.1242/dev.199686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380467/
https://www.ncbi.nlm.nih.gov/pubmed/34355730
http://dx.doi.org/10.1242/dev.199686

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