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Fis1 ablation in the male germline disrupts mitochondrial morphology and mitophagy, and arrests spermatid maturation
Male germline development involves choreographed changes to mitochondrial number, morphology and organization. Mitochondrial reorganization during spermatogenesis was recently shown to require mitochondrial fusion and fission. Mitophagy, the autophagic degradation of mitochondria, is another mechani...
Autores principales: | Varuzhanyan, Grigor, Ladinsky, Mark S., Yamashita, Shun-ichi, Abe, Manabu, Sakimura, Kenji, Kanki, Tomotake, Chan, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380467/ https://www.ncbi.nlm.nih.gov/pubmed/34355730 http://dx.doi.org/10.1242/dev.199686 |
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