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Vaccine design and delivery approaches for COVID-19

COVID-19 is still a deadly disease that remains yet a major challenge for humans. In recent times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of time and cost in fighting this disease. In this regard, today's scientific knowledge shows that designing and prod...

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Autores principales: Shahzamani, Kiana, Mahmoudian, Fatemeh, Ahangarzadeh, Shahrzad, Ranjbar, Mohammad Mehdi, Beikmohammadi, Leila, Bahrami, Samira, Mohammadi, Elmira, Esfandyari, Sahar, Alibakhshi, Abbas, Javanmard, Shaghayegh Haghjooy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380485/
https://www.ncbi.nlm.nih.gov/pubmed/34454291
http://dx.doi.org/10.1016/j.intimp.2021.108086
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author Shahzamani, Kiana
Mahmoudian, Fatemeh
Ahangarzadeh, Shahrzad
Ranjbar, Mohammad Mehdi
Beikmohammadi, Leila
Bahrami, Samira
Mohammadi, Elmira
Esfandyari, Sahar
Alibakhshi, Abbas
Javanmard, Shaghayegh Haghjooy
author_facet Shahzamani, Kiana
Mahmoudian, Fatemeh
Ahangarzadeh, Shahrzad
Ranjbar, Mohammad Mehdi
Beikmohammadi, Leila
Bahrami, Samira
Mohammadi, Elmira
Esfandyari, Sahar
Alibakhshi, Abbas
Javanmard, Shaghayegh Haghjooy
author_sort Shahzamani, Kiana
collection PubMed
description COVID-19 is still a deadly disease that remains yet a major challenge for humans. In recent times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of time and cost in fighting this disease. In this regard, today's scientific knowledge shows that designing and producing an effective vaccine is the best possible way to diminish the disease burden and dissemination or even eradicate the disease. Due to the urgent need, many vaccines are now available earlier than scheduled. New technologies have also helped to produce much more effective vaccines, although the potential side effects must be taken into account. Thus, in this review, the types of vaccines and vaccine designs made against COVID-19, the vaccination programs, as well as the delivery methods and molecules that have been used to deliver some vaccines that need a carrier will be described.
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spelling pubmed-83804852021-08-23 Vaccine design and delivery approaches for COVID-19 Shahzamani, Kiana Mahmoudian, Fatemeh Ahangarzadeh, Shahrzad Ranjbar, Mohammad Mehdi Beikmohammadi, Leila Bahrami, Samira Mohammadi, Elmira Esfandyari, Sahar Alibakhshi, Abbas Javanmard, Shaghayegh Haghjooy Int Immunopharmacol Article COVID-19 is still a deadly disease that remains yet a major challenge for humans. In recent times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of time and cost in fighting this disease. In this regard, today's scientific knowledge shows that designing and producing an effective vaccine is the best possible way to diminish the disease burden and dissemination or even eradicate the disease. Due to the urgent need, many vaccines are now available earlier than scheduled. New technologies have also helped to produce much more effective vaccines, although the potential side effects must be taken into account. Thus, in this review, the types of vaccines and vaccine designs made against COVID-19, the vaccination programs, as well as the delivery methods and molecules that have been used to deliver some vaccines that need a carrier will be described. Elsevier B.V. 2021-11 2021-08-23 /pmc/articles/PMC8380485/ /pubmed/34454291 http://dx.doi.org/10.1016/j.intimp.2021.108086 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Shahzamani, Kiana
Mahmoudian, Fatemeh
Ahangarzadeh, Shahrzad
Ranjbar, Mohammad Mehdi
Beikmohammadi, Leila
Bahrami, Samira
Mohammadi, Elmira
Esfandyari, Sahar
Alibakhshi, Abbas
Javanmard, Shaghayegh Haghjooy
Vaccine design and delivery approaches for COVID-19
title Vaccine design and delivery approaches for COVID-19
title_full Vaccine design and delivery approaches for COVID-19
title_fullStr Vaccine design and delivery approaches for COVID-19
title_full_unstemmed Vaccine design and delivery approaches for COVID-19
title_short Vaccine design and delivery approaches for COVID-19
title_sort vaccine design and delivery approaches for covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380485/
https://www.ncbi.nlm.nih.gov/pubmed/34454291
http://dx.doi.org/10.1016/j.intimp.2021.108086
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