Exenatide Attenuates Obesity-Induced Mitochondrial Dysfunction by Activating SIRT1 in Renal Tubular Cells

Saturated free fatty acid (FFA)-induced lipotoxicity plays an important role in obesity-induced kidney injury. Exenatide, a Glucagon-like peptide-1 receptor agonist(GLP-1RA), protects against high-fat diet (HFD)-induced kidney injury. The precise mechanism needs to be further explored. This study in...

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Detalles Bibliográficos
Autores principales: Wang, Yao, He, Wei, Wei, Wei, Mei, Xiaoxue, Yang, Ming, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380782/
https://www.ncbi.nlm.nih.gov/pubmed/34434166
http://dx.doi.org/10.3389/fendo.2021.622737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380782/
https://www.ncbi.nlm.nih.gov/pubmed/34434166
http://dx.doi.org/10.3389/fendo.2021.622737

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