SARS-CoV-2 on the ocular surface: is it truly a novel transmission route?

Since December 2019, the novel COVID-19 outbreak has spread rapidly around the globe and infected millions of people. Although the major transmission route of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is considered to be airborne droplets and close contact, the ocular transmission...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xuhui, Yu, Huimin, Mei, Ting, Chen, Bo, Chen, Liwen, Li, Shanling, Zhang, Xian, Sun, Xufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380887/
https://www.ncbi.nlm.nih.gov/pubmed/32788324
http://dx.doi.org/10.1136/bjophthalmol-2020-316263
_version_ 1783741262828929024
author Chen, Xuhui
Yu, Huimin
Mei, Ting
Chen, Bo
Chen, Liwen
Li, Shanling
Zhang, Xian
Sun, Xufang
author_facet Chen, Xuhui
Yu, Huimin
Mei, Ting
Chen, Bo
Chen, Liwen
Li, Shanling
Zhang, Xian
Sun, Xufang
author_sort Chen, Xuhui
collection PubMed
description Since December 2019, the novel COVID-19 outbreak has spread rapidly around the globe and infected millions of people. Although the major transmission route of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is considered to be airborne droplets and close contact, the ocular transmission route has been reported with great concern. The current work summarises the characteristics of SARS-CoV-2, the ocular distribution of the major SARS-CoV-2 binding protein, and the experimental and clinical evidence of the ocular transmission route. Although it seems that the likelihood of the ocular surface being an infection gateway is low, SARS-CoV-2 infection or transmission via the ocular surface may cause conjunctivitis and other ocular discomfort. Therefore, good eye protection is an essential safeguard procedure, especially for medical staff.
format Online
Article
Text
id pubmed-8380887
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-83808872021-09-08 SARS-CoV-2 on the ocular surface: is it truly a novel transmission route? Chen, Xuhui Yu, Huimin Mei, Ting Chen, Bo Chen, Liwen Li, Shanling Zhang, Xian Sun, Xufang Br J Ophthalmol Review Since December 2019, the novel COVID-19 outbreak has spread rapidly around the globe and infected millions of people. Although the major transmission route of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is considered to be airborne droplets and close contact, the ocular transmission route has been reported with great concern. The current work summarises the characteristics of SARS-CoV-2, the ocular distribution of the major SARS-CoV-2 binding protein, and the experimental and clinical evidence of the ocular transmission route. Although it seems that the likelihood of the ocular surface being an infection gateway is low, SARS-CoV-2 infection or transmission via the ocular surface may cause conjunctivitis and other ocular discomfort. Therefore, good eye protection is an essential safeguard procedure, especially for medical staff. BMJ Publishing Group 2021-09 2020-07-08 /pmc/articles/PMC8380887/ /pubmed/32788324 http://dx.doi.org/10.1136/bjophthalmol-2020-316263 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Review
Chen, Xuhui
Yu, Huimin
Mei, Ting
Chen, Bo
Chen, Liwen
Li, Shanling
Zhang, Xian
Sun, Xufang
SARS-CoV-2 on the ocular surface: is it truly a novel transmission route?
title SARS-CoV-2 on the ocular surface: is it truly a novel transmission route?
title_full SARS-CoV-2 on the ocular surface: is it truly a novel transmission route?
title_fullStr SARS-CoV-2 on the ocular surface: is it truly a novel transmission route?
title_full_unstemmed SARS-CoV-2 on the ocular surface: is it truly a novel transmission route?
title_short SARS-CoV-2 on the ocular surface: is it truly a novel transmission route?
title_sort sars-cov-2 on the ocular surface: is it truly a novel transmission route?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380887/
https://www.ncbi.nlm.nih.gov/pubmed/32788324
http://dx.doi.org/10.1136/bjophthalmol-2020-316263
work_keys_str_mv AT chenxuhui sarscov2ontheocularsurfaceisittrulyanoveltransmissionroute
AT yuhuimin sarscov2ontheocularsurfaceisittrulyanoveltransmissionroute
AT meiting sarscov2ontheocularsurfaceisittrulyanoveltransmissionroute
AT chenbo sarscov2ontheocularsurfaceisittrulyanoveltransmissionroute
AT chenliwen sarscov2ontheocularsurfaceisittrulyanoveltransmissionroute
AT lishanling sarscov2ontheocularsurfaceisittrulyanoveltransmissionroute
AT zhangxian sarscov2ontheocularsurfaceisittrulyanoveltransmissionroute
AT sunxufang sarscov2ontheocularsurfaceisittrulyanoveltransmissionroute

Ejemplares similares