Risk Factors for Development and Severity of COVID-19 in COPD Patients

The impact that COVID-19 could have on patients with COPD is a real concern. In this study we evaluated, in a cohort of longitudinally followed COPD subjects, the incidence of COVID-19, seeking for possible risk factors and prognostic factors predicting the clinical outcome. In our cohort of 370 pat...

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Detalles Bibliográficos
Autores principales: Bonato, Matteo, Semenzato, Umberto, Tinè, Mariaenrica, Bazzan, Erica, Damin, Marco, Biondini, Davide, Casara, Alvise, Romagnoli, Micaela, Turato, Graziella, Cosio, Manuel G., Saetta, Marina, Baraldo, Simonetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380950/
https://www.ncbi.nlm.nih.gov/pubmed/34434947
http://dx.doi.org/10.3389/fmed.2021.714570
Descripción
Sumario:The impact that COVID-19 could have on patients with COPD is a real concern. In this study we evaluated, in a cohort of longitudinally followed COPD subjects, the incidence of COVID-19, seeking for possible risk factors and prognostic factors predicting the clinical outcome. In our cohort of 370 patients (followed for 5.3 ± 2.7 years), 22 developed COVID-19 (COPD/COVID-19+) between February/November 2020 (5.9%). Cardio-metabolic conditions (hypertension, dyslipidemia, obesity, diabetes) but not respiratory abnormalities (FEV(1), DLCO, emphysema and exacerbation history), were risk factors for development of COVID-19 in COPD patients. Out of the 22 COPD/COVID-19+ patients, 10 needed intensive care. Low DLCO and emphysema, but also metabolic comorbidities, were related to the need for intensive care.

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