Cargando…

Tilianin inhibits the human ovarian cancer (PA-1) cell proliferation via blocking cell cycle, inducing apoptosis and inhibiting JAK2/STAT3 signaling pathway

Ovarian cancer is one of the deadliest gynecologic malignancies and is the seventh leading cause of mortalities and morbidities globally. Although there are various therapeutic strategies, a major challenge for scientific community is to come up with effective strategy to treat ovarian cancer. Tilia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Chunqiu, Yan, Bingbing, Xia, Suhua, Yu, Fei, Zhao, Jingjing, Bai, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381034/ https://www.ncbi.nlm.nih.gov/pubmed/34466064 http://dx.doi.org/10.1016/j.sjbs.2021.06.033

Ejemplares similares

ST8SIA1 inhibits the proliferation, migration and invasion of bladder cancer cells by blocking the JAK/STAT signaling pathway
por: Yu, Shengjin, et al.
Publicado: (2021)

Atheroprotective Mechanisms of Tilianin by Inhibiting Inflammation Through Down-Regulating NF-κB Pathway and Foam Cells Formation
por: Shen, Wanli, et al.
Publicado: (2019)

Blocking Jak/STAT signalling using tofacitinib inhibits angiogenesis in experimental arthritis
por: Di Benedetto, Paola, et al.
Publicado: (2021)

Tilianin Post-Conditioning Attenuates Myocardial Ischemia/Reperfusion Injury via Mitochondrial Protection and Inhibition of Apoptosis
por: Wang, Yangyang, et al.
Publicado: (2017)

Fraxetin Inhibits the Proliferation and Metastasis of Glioma Cells by Inactivating JAK2/STAT3 Signaling
por: Qu, Liangchen, et al.
Publicado: (2021)

Lestaurtinib Inhibition of the JAK/STAT Signaling Pathway in Hodgkin Lymphoma Inhibits Proliferation and Induces Apoptosis
por: Diaz, Tania, et al.
Publicado: (2011)

Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling
por: Xiong, Hua, et al.
Publicado: (2009)

HLX affects cell cycle and proliferation in AML cells via the JAK/STAT signaling pathway
por: Zhu, Xia-Yin, et al.
Publicado: (2020)

Ruxolitinib inhibits the proliferation and induces the apoptosis of MLL-r ALL cells through inactivating JAK/STAT signaling pathway
por: Liao, Xiong-Yu, et al.
Publicado: (2023)

An overview of JAK/STAT pathways and JAK inhibition in alopecia areata
por: Lensing, Maddison, et al.
Publicado: (2022)

Centipeda minima Extract Inhibits Inflammation and Cell Proliferation by Regulating JAK/STAT Signaling in Macrophages and Keratinocytes
por: Ma, Yuanqiang, et al.
Publicado: (2023)

Inhibition of JAK/STAT signaling stimulates adult satellite cell function
por: Price, Feodor D., et al.
Publicado: (2014)

LIF Inhibits Proliferation of Esophageal Squamous Carcinoma Cells by Radiation Mediated Through JAK-STAT Signaling Pathway
por: Luo, Hongtao, et al.
Publicado: (2023)

Resveratrol Induces Cell Cycle Arrest and Apoptosis in Malignant NK Cells via JAK2/STAT3 Pathway Inhibition
por: Quoc Trung, Ly, et al.
Publicado: (2013)

A review of JAK–STAT signalling in the pathogenesis of spondyloarthritis and the role of JAK inhibition
por: McInnes, Iain B, et al.
Publicado: (2021)

Long Noncoding RNA FEZF1-AS1 Promotes Proliferation and Inhibits Apoptosis in Ovarian Cancer by Activation of JAK-STAT3 Pathway
por: Zhao, Xia, et al.
Publicado: (2018)

The molecular basis of JAK/STAT inhibition by SOCS1
por: Liau, Nicholas P. D., et al.
Publicado: (2018)

Scutellarin inhibits proliferation and invasion of hepatocellular carcinoma cells via down‐regulation of JAK2/STAT3 pathway
por: Liu, Kang, et al.
Publicado: (2019)

Icaritin Inhibits JAK/STAT3 Signaling and Growth of Renal Cell Carcinoma
por: Li, Shasha, et al.
Publicado: (2013)

Interleukin-6 Blocking vs. JAK-STAT Inhibition for Prevention of Lung Injury in Patients with COVID-19
por: Meletiadis, Joseph, et al.
Publicado: (2020)

Cannabis suppresses antitumor immunity by inhibiting JAK/STAT signaling in T cells through CNR2
por: Xiong, Xinxin, et al.
Publicado: (2022)

Silencing of lncRNA LINC00346 Inhibits the Proliferation and Promotes the Apoptosis of Colorectal Cancer Cells Through Inhibiting JAK1/STAT3 Signaling
por: Li, Dan, et al.
Publicado: (2020)

Knockdown of HE4 suppresses aggressive cell growth and malignant progression of ovarian cancer by inhibiting the JAK/STAT3 pathway
por: Wang, Aihong, et al.
Publicado: (2019)

Inhibition of JAK2/STAT3 Signaling Pathway Suppresses Proliferation of Burkitt’s Lymphoma Raji Cells via Cell Cycle Progression, Apoptosis, and Oxidative Stress by Modulating HSP70
por: Xu, Neng-Wen, et al.
Publicado: (2018)

Berberine downregulates CDC6 and inhibits proliferation via targeting JAK-STAT3 signaling in keratinocytes
por: Sun, Shuna, et al.
Publicado: (2019)

Astaxanthin Inhibits JAK/STAT-3 Signaling to Abrogate Cell Proliferation, Invasion and Angiogenesis in a Hamster Model of Oral Cancer
por: Kowshik, J., et al.
Publicado: (2014)

Curcumin inhibits the proliferation and invasion of MG-63 cells through inactivation of the p-JAK2/p-STAT3 pathway
por: Sun, Yuanjue, et al.
Publicado: (2019)

Cell Death by Gallotannin Is Associated with Inhibition of the JAK/STAT Pathway in Human Colon Cancer Cells
por: Houssein, Marwa, et al.
Publicado: (2020)

Curcumin induces apoptosis in JAK2‐mutated cells by the inhibition of JAK2/STAT and mTORC1 pathways
por: Petiti, Jessica, et al.
Publicado: (2019)

The Nucleoprotein and Phosphoprotein of Peste des Petits Ruminants Virus Inhibit Interferons Signaling by Blocking the JAK-STAT Pathway
por: Li, Pengfei, et al.
Publicado: (2019)

Curcumol may alleviate psoriasis-like inflammation by inhibiting keratinocyte proliferation and inflammatory gene expression via JAK1/STAT3 signaling
por: Lv, Mingfen, et al.
Publicado: (2021)

Pharmacologic inhibition of JAK-STAT signaling promotes hair growth
por: Harel, Sivan, et al.
Publicado: (2015)

Pharmacological inhibition of demethylzeylasteral on JAK-STAT signaling ameliorates vitiligo
por: Chang, Yuqian, et al.
Publicado: (2023)

Crocin promotes apoptosis of human skin cancer cells by inhibiting the JAK/STAT pathway
por: Wang, Gongfeng, et al.
Publicado: (2018)

Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma
por: Yang, Shuqun, et al.
Publicado: (2015)

Silencing of lncRNA LINC00346 Inhibits the Proliferation and Promotes the Apoptosis of Colorectal Cancer Cells Through Inhibiting JAK1/STAT3 Signaling [Retraction]
Publicado: (2020)

Aspirin Inhibits Carcinogenesis of Intestinal Mucosal Cells in UC Mice Through Inhibiting IL-6/JAK/STAT3 Signaling Pathway and Modulating Apoptosis and Proliferation
por: Chen, Yingying, et al.
Publicado: (2022)

3C(pro) of FMDV inhibits type II interferon-stimulated JAK-STAT signaling pathway by blocking STAT1 nuclear translocation
por: Wu, Xiangju, et al.
Publicado: (2023)

Plumericin inhibits proliferation of vascular smooth muscle cells by blocking STAT3 signaling via S-glutathionylation
por: Heiss, Elke H, et al.
Publicado: (2016)

CHAF1A promotes the proliferation and growth of epithelial ovarian cancer cells by affecting the phosphorylation of JAK2/STAT3 signaling pathway
por: Xia, Dandan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_vlkhg9dlq07ibg2jomq6m7m770