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Dynamic Network Biomarker of Pre-Exhausted CD8(+) T Cells Contributed to T Cell Exhaustion in Colorectal Cancer

Immunotherapy has achieved positive clinical responses in various cancers. However, in advanced colorectal cancer (CRC), immunotherapy is challenging because of the deterioration of T-cell exhaustion, the mechanism of which is still unclear. In this study, we depicted CD8(+) T-cell developmental tra...

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Detalles Bibliográficos
Autores principales:	Hu, Jiaqi, Han, Chongyin, Zhong, Jiayuan, Liu, Huisheng, Liu, Rui, Luo, Wei, Chen, Pei, Ling, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381053/ https://www.ncbi.nlm.nih.gov/pubmed/34434188 http://dx.doi.org/10.3389/fimmu.2021.691142

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