RUNX1 mutation and elevated FLT3 gene expression cooperates to induce inferior prognosis in cytogenetically normal acute myeloid leukemia patients

BACKGROUND: Acute myeloid leukemia (AML) is a bone marrow malignancy having multiple molecular pathways driving its progress. In recent years, the main causes of AML considered all over the world are genetic variations in cancerous cells. The RUNX1 and FLT3 genes are necessary for the normal hematop...

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Detalles Bibliográficos
Autores principales: Rehman, Atia, Akram, Afia Muhammad, Chaudhary, Asma, Sheikh, Nadeem, Hussain, Zawar, Alsanie, Walaa F., Rehman, Rahat Abdul, Hameed, Naila, Saleem, Tayyaba, Zafar, Amjad, Absar, Muhammad, Iqbal, Zafar, Alhazmi, Alaa, Baeshen, Hosam Ali, Mohammedsaleh, Zuhair M, Qamer, Samina, Sayed, Samy, Gaber, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381075/
https://www.ncbi.nlm.nih.gov/pubmed/34466057
http://dx.doi.org/10.1016/j.sjbs.2021.07.012

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