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Tumor Cells Detected in Retrieved Thrombus: Cancer-associated Stroke

A 51-year-old man with a history of renal cell carcinoma presented with sudden aphasia, right hemiparesis, and dysesthesia. MRA showed left middle cerebral artery occlusion, and he was diagnosed with acute ischemic stroke and treated with intravenous recombinant tissue plasminogen activator and endo...

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Detalles Bibliográficos
Autores principales: Nakanishi, Kaoru, Kawano, Hiroyuki, Yamagishi, Yuki, Kamma, Hiroshi, Shiokawa, Yoshiaki, Hirano, Teruyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381188/
https://www.ncbi.nlm.nih.gov/pubmed/33678737
http://dx.doi.org/10.2169/internalmedicine.6201-20
Descripción
Sumario:A 51-year-old man with a history of renal cell carcinoma presented with sudden aphasia, right hemiparesis, and dysesthesia. MRA showed left middle cerebral artery occlusion, and he was diagnosed with acute ischemic stroke and treated with intravenous recombinant tissue plasminogen activator and endovascular thrombectomy. The pathological diagnosis of the retrieved thrombus was consistent with the already-known pathological findings of the primary renal cell carcinoma. Therefore, a diagnosis of cerebral embolism caused by tumor cells was made. The pathological findings of the retrieved thrombi were important in determining the cause of ischemic stroke.