Host polymorphisms and COVID-19 infection

Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus, severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). There is growing evidence that host genetics play an important role in COVID-19 severity. Based on current knowledge about the human protein...

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Detalles Bibliográficos
Autores principales: Delanghe, Joris R., Speeckaert, Marijn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381193/
https://www.ncbi.nlm.nih.gov/pubmed/35337605
http://dx.doi.org/10.1016/bs.acc.2021.07.002
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author Delanghe, Joris R.
Speeckaert, Marijn M.
author_facet Delanghe, Joris R.
Speeckaert, Marijn M.
author_sort Delanghe, Joris R.
collection PubMed
description Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus, severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). There is growing evidence that host genetics play an important role in COVID-19 severity. Based on current knowledge about the human protein machinery for SARS-CoV-2 entry, the host innate immune response, and virus-host interactions, the potential effects of human genetic polymorphisms, which may contribute to clinical differences in SARS-CoV-2 pathogenesis, may help to determine the individual risk for COVID-19 infection and outcome.
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spelling pubmed-83811932021-08-23 Host polymorphisms and COVID-19 infection Delanghe, Joris R. Speeckaert, Marijn M. Adv Clin Chem Article Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus, severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). There is growing evidence that host genetics play an important role in COVID-19 severity. Based on current knowledge about the human protein machinery for SARS-CoV-2 entry, the host innate immune response, and virus-host interactions, the potential effects of human genetic polymorphisms, which may contribute to clinical differences in SARS-CoV-2 pathogenesis, may help to determine the individual risk for COVID-19 infection and outcome. Elsevier Inc. 2022 2021-08-23 /pmc/articles/PMC8381193/ /pubmed/35337605 http://dx.doi.org/10.1016/bs.acc.2021.07.002 Text en Copyright © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Delanghe, Joris R.
Speeckaert, Marijn M.
Host polymorphisms and COVID-19 infection
title Host polymorphisms and COVID-19 infection
title_full Host polymorphisms and COVID-19 infection
title_fullStr Host polymorphisms and COVID-19 infection
title_full_unstemmed Host polymorphisms and COVID-19 infection
title_short Host polymorphisms and COVID-19 infection
title_sort host polymorphisms and covid-19 infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381193/
https://www.ncbi.nlm.nih.gov/pubmed/35337605
http://dx.doi.org/10.1016/bs.acc.2021.07.002
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