Primary Immune Responses and Affinity Maturation Are Controlled by IgD

Mature B cells co-express IgM and IgD B cell antigen receptors (BCR) on their surface. While IgM BCR expression is already essential at early stages of development, the role of the IgD-class BCR remains unclear as most B cell functions appeared unchanged in IgD-deficient mice. Here, we show that IgD...

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Detalles Bibliográficos
Autores principales: Amendt, Timm, Ayoubi, Omar El, Linder, Alexandra T., Allies, Gabriele, Young, Marc, Setz, Corinna S., Jumaa, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381280/
https://www.ncbi.nlm.nih.gov/pubmed/34434193
http://dx.doi.org/10.3389/fimmu.2021.709240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381280/
https://www.ncbi.nlm.nih.gov/pubmed/34434193
http://dx.doi.org/10.3389/fimmu.2021.709240

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