Cargando…

Blockade of BK channels attenuates chronic visceral hypersensitivity in an IBS-like rat model

BACKGROUND: Visceral hypersensitivity in irritable bowel syndrome (IBS) is still poorly understood, despite that chronic abdominal pain is the most common symptoms in IBS patients. To study effects of BK channels on visceral hypersensitivity in IBS rats and the underlying mechanisms, IBS rats were e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, F, Chen, Y, Chen, Z, Guan, L, Ye, Z, Tang, Y, Chen, A, Lin, C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381452/ https://www.ncbi.nlm.nih.gov/pubmed/34407673 http://dx.doi.org/10.1177/17448069211040364

Ejemplares similares

Blockade of BDNF signalling attenuates chronic visceral hypersensitivity in an IBS‐like rat model
por: Fan, Fei, et al.
Publicado: (2020)

Integrated omics analysis reveals the epigenetic mechanism of visceral hypersensitivity in IBS-D
por: Lu, Yaoyao, et al.
Publicado: (2023)

The Importance of Visceral Hypersensitivity in Irritable Bowel Syndrome—Plant Metabolites in IBS Treatment
por: Dudzińska, Ewa, et al.
Publicado: (2023)

Electroacupuncture Attenuates Post-Inflammatory IBS-Associated Visceral and Somatic Hypersensitivity and Correlates With the Regulatory Mechanism of Epac1–Piezo2 Axis
por: Guo, Jing, et al.
Publicado: (2022)

Neuro-Immune Modulation Effects of Sacral Nerve Stimulation for Visceral Hypersensitivity in Rats
por: Jin, Xue, et al.
Publicado: (2021)

Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway
por: Jiang, Tianyuan, et al.
Publicado: (2022)

Electroacupuncture and Moxibustion Modulate the BDNF and TrkB Expression in the Colon and Dorsal Root Ganglia of IBS Rats with Visceral Hypersensitivity
por: Jin, Duiyin, et al.
Publicado: (2021)

Corrigendum: Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway
por: Jiang, Tianyuan, et al.
Publicado: (2022)

Electroacupuncture Alleviates Visceral Hypersensitivity in IBS-D Rats by Inhibiting EGCs Activity through Regulating BDNF/TrkB Signaling Pathway
por: Zhao, Ying, et al.
Publicado: (2022)

Effect of acupuncture and its influence on visceral hypersensitivity in IBS-D patients: Study protocol for a randomized controlled trial
por: Pei, Lixia, et al.
Publicado: (2018)

Electroacupuncture Improves IBS Visceral Hypersensitivity by Inhibiting the Activation of Astrocytes in the Medial Thalamus and Anterior Cingulate Cortex
por: Zhao, Min, et al.
Publicado: (2020)

Enhancement Effects of Martentoxin on Glioma BK Channel and BK Channel (α+β1) Subtypes
por: Tao, Jie, et al.
Publicado: (2011)

Attenuated BK channel function promotes overactive bladder in a rat model of obesity
por: Li, Ning, et al.
Publicado: (2019)

Elevated expression of c-fos in central nervous system correlates with visceral hypersensitivity in irritable bowel syndrome (IBS): a new target for IBS treatment
por: Zhang, Ru, et al.
Publicado: (2011)

BDNF contributes to IBS-like colonic hypersensitivity via activating the enteroglia-nerve unit
por: Wang, Peng, et al.
Publicado: (2016)

Hydrophobic gating in BK channels
por: Jia, Zhiguang, et al.
Publicado: (2018)

Activating metabotropic glutamate receptor-7 attenuates visceral hypersensitivity in neonatal maternally separated rats
por: Shao, Limei, et al.
Publicado: (2019)

Study on the Mechanism Underlying the Regulation of the NMDA Receptor Pathway in Spinal Dorsal Horns of Visceral Hypersensitivity Rats by Moxibustion
por: Wang, L. D., et al.
Publicado: (2016)

BK K(+) channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells
por: Edalat, Lena, et al.
Publicado: (2016)

Zeta Inhibitory Peptide as a Novel Therapy to Control Chronic Visceral Hypersensitivity in a Rat Model
por: Tang, Ying, et al.
Publicado: (2016)

Toll-Like Receptor 4 in Paraventricular Nucleus Mediates Visceral Hypersensitivity Induced by Maternal Separation
por: Tang, Hui-Li, et al.
Publicado: (2017)

Author Correction: BDNF contributes to IBS-like colonic hypersensitivity via activating the enteroglia-nerve unit
por: Wang, Peng, et al.
Publicado: (2021)

Oral treatment with plecanatide or dolcanatide attenuates visceral hypersensitivity via activation of guanylate cyclase-C in rat models
por: Boulete, Illona-Marie, et al.
Publicado: (2018)

Baifuzi reduces transient ischemic brain damage through an interaction with the STREX domain of BK(Ca) channels
por: Chi, S, et al.
Publicado: (2010)

Publisher Correction: Hydrophobic gating in BK channels
por: Jia, Zhiguang, et al.
Publicado: (2020)

Main ion channels and receptors associated with visceral hypersensitivity in irritable bowel syndrome
por: de Carvalho Rocha, Heraldo Arcela, et al.
Publicado: (2014)

Contribution of Amygdala Histone Acetylation in Early Life Stress-Induced Visceral Hypersensitivity and Emotional Comorbidity
por: Guan, Le, et al.
Publicado: (2022)

Blockage of High-Affinity Choline Transporter Increases Visceral Hypersensitivity in Rats with Chronic Stress
por: Zhao, Chen, et al.
Publicado: (2018)

Mitochondrial BK(Ca) channel
por: Balderas, Enrique, et al.
Publicado: (2015)

Involvement of protein kinase ζ in the maintenance of hippocampal long-term potentiation in rats with chronic visceral hypersensitivity
por: Chen, Aiqin, et al.
Publicado: (2015)

Auricular Vagus Nerve Stimulation Improves Visceral Hypersensitivity and Gastric Motility and Depression-like Behaviors via Vago-Vagal Pathway in a Rat Model of Functional Dyspepsia
por: Hou, Liwei, et al.
Publicado: (2023)

BK Polyomavirus Subtypes IVc-1 and Ib-1 in Vietnamese Renal Transplant Recipients
por: Dinh, Hang Thi Thu, et al.
Publicado: (2021)

Role of voltage gated Ca(2+) channels in rat visceral hypersensitivity change induced by 2,4,6-trinitrobenzene sulfonic acid
por: Qian, Aihua, et al.
Publicado: (2013)

Allosteric-activation mechanism of BK channel gating ring triggered by calcium ions
por: Guan, Ronghua, et al.
Publicado: (2017)

Complete Genome Sequence of BK Polyomavirus Subtype Ib-1 Detected in a Kidney Transplant Patient with BK Viremia Using Shotgun Sequencing
por: Ranjan, Ravi, et al.
Publicado: (2017)

Electroacupuncture at ST36 Relieves Visceral Hypersensitivity via the NGF/TrkA/TRPV1 Peripheral Afferent Pathway in a Rodent Model of Post-Inflammation Rectal Hypersensitivity
por: Chen, Yan, et al.
Publicado: (2021)

BK channel blocker paxilline attenuates thalidomide-caused synaptic and cognitive dysfunctions in mice
por: Choi, Tae-Yong, et al.
Publicado: (2018)

Facilitation of Synaptic Transmission in the Anterior Cingulate Cortex in Viscerally Hypersensitive Rats
por: Wang, Jun, et al.
Publicado: (2015)

Visceral Hypersensitivity and Altered Colonic Motility in Type 2 Diabetic Rat
por: Sung, Tae Sik, et al.
Publicado: (2015)

Vasodilation of rat skeletal muscle arteries by the novel BK channel opener GoSlo is mediated by the simultaneous activation of BK and K(v)7 channels
por: Zavaritskaya, Olga, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_d1v16or87b7umeh648r95uu0pl