INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants

Genome-wide association studies reveal many non-coding variants associated with complex traits. However, model organism studies largely remain as an untapped resource for unveiling the effector genes of non-coding variants. We develop INFIMA, Integrative Fine-Mapping, to pinpoint causal SNPs for div...

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Detalles Bibliográficos
Autores principales: Dong, Chenyang, Simonett, Shane P., Shin, Sunyoung, Stapleton, Donnie S., Schueler, Kathryn L., Churchill, Gary A., Lu, Leina, Liu, Xiaoxiao, Jin, Fulai, Li, Yan, Attie, Alan D., Keller, Mark P., Keleş, Sündüz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381555/
https://www.ncbi.nlm.nih.gov/pubmed/34425882
http://dx.doi.org/10.1186/s13059-021-02450-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381555/
https://www.ncbi.nlm.nih.gov/pubmed/34425882
http://dx.doi.org/10.1186/s13059-021-02450-8

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