Cargando…

Inflammatory gene expression profiling in peripheral blood from patients with Alzheimer’s disease reveals key pathways and hub genes with potential diagnostic utility: a preliminary study

BACKGROUND: Alzheimer’s disease (AD) is an age-related neurodegenerative disease caused by central nervous system disorders. Late-onset Alzheimer disease (LOAD) is the most common neurodegenerative disorder worldwide. Differences at the expression level of certain genes, resulting from either geneti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cardona, Kelly, Medina, Javier, Orrego-Cardozo, Mary, Restrepo de Mejía, Francia, Elcoroaristizabal, Xabier, Naranjo Galvis, Carlos Andrés
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2021
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381883/ https://www.ncbi.nlm.nih.gov/pubmed/34484988 http://dx.doi.org/10.7717/peerj.12016

Ejemplares similares

Toxoplasma gondii infection and peripheral-blood gene expression profiling of older people reveals dysregulation of cytokines and identifies hub genes as potential therapeutic targets
por: Naranjo-Galvis, Carlos A., et al.
Publicado: (2022)

Identification of key gene modules and hub genes of human mantle cell lymphoma by coexpression network analysis
por: Guo, Dongmei, et al.
Publicado: (2020)

Identification of key modules and hub genes associated with lung function in idiopathic pulmonary fibrosis
por: Xia, Yuechong, et al.
Publicado: (2020)

Identification of hub genes related to prognosis in glioma
por: Zhang, Delong, et al.
Publicado: (2020)

Identification and validation of key modules and hub genes associated with the pathological stage of oral squamous cell carcinoma by weighted gene co-expression network analysis
por: Hu, Xuegang, et al.
Publicado: (2020)

Entamoeba histolytica HM-1: IMSS gene expression profiling identifies key hub genes, potential biomarkers, and pathways in Amoebiasis infection: a systematic network meta-analysis
por: Verma, Ram Nayan, et al.
Publicado: (2022)

Identification of the hub genes in gastric cancer through weighted gene co-expression network analysis
por: Li, Chunyang, et al.
Publicado: (2021)

Identification of four hub genes associated with adrenocortical carcinoma progression by WGCNA
por: Xia, Wang-Xiao, et al.
Publicado: (2019)

Identification of key genes associated with multiple sclerosis based on gene expression data from peripheral blood mononuclear cells
por: Shang, Zhenwei, et al.
Publicado: (2020)

Identification of hub genes and biological pathways in hepatocellular carcinoma by integrated bioinformatics analysis
por: Zhao, Qian, et al.
Publicado: (2021)

Hub gene associated with prognosis in bladder cancer is a novel therapeutic target
por: Fang, Dengpan, et al.
Publicado: (2023)

Identification of hub genes and potential molecular mechanisms in gastric cancer by integrated bioinformatics analysis
por: Cao, Ling, et al.
Publicado: (2018)

Identification of hub genes and small-molecule compounds related to intracerebral hemorrhage with bioinformatics analysis
por: Liu, Zhendong, et al.
Publicado: (2019)

Integrated bioinformatics analysis for the identification of hub genes and signaling pathways related to circANRIL
por: Qin, Qiuyan, et al.
Publicado: (2022)

CD36 identified by weighted gene co-expression network analysis as a hub candidate gene in lupus nephritis
por: Yang, Huiying, et al.
Publicado: (2019)

Identification of key genes and validation of key gene aquaporin 1 on Wilms’ tumor metastasis
por: Liu, Hong, et al.
Publicado: (2023)

Identifying hub genes of papillary thyroid carcinoma in the TCGA and GEO database using bioinformatics analysis
por: Wan, Ying, et al.
Publicado: (2020)

Significance of hub genes and immune cell infiltration identified by bioinformatics analysis in pelvic organ prolapse
por: Zhao, Ying, et al.
Publicado: (2020)

Bioinformatics analysis and identification of hub genes and immune-related molecular mechanisms in chronic myeloid leukemia
por: Yao, Fangyi, et al.
Publicado: (2022)

Identification and validation of hub genes involved in foam cell formation and atherosclerosis development via bioinformatics
por: Teng, Da, et al.
Publicado: (2023)

Identification of the hub gene BUB1B in hepatocellular carcinoma via bioinformatic analysis and in vitro experiments
por: Fu, Jie, et al.
Publicado: (2021)

Identifying DUSP-1 and FOSB as hub genes in immunoglobulin A nephropathy by WGCNA and DEG screening and validation
por: Jianping, Wu, et al.
Publicado: (2022)

Identification of hub genes in colorectal cancer based on weighted gene co-expression network analysis and clinical data from The Cancer Genome Atlas
por: Zhang, Yu, et al.
Publicado: (2021)

Identifying liver metastasis-related hub genes in breast cancer and characterizing SPARCL1 as a potential prognostic biomarker
por: Chen, Mingkuan, et al.
Publicado: (2023)

ceRNA network construction and identification of hub genes as novel therapeutic targets for age-related cataracts using bioinformatics
por: Hong, Yingying, et al.
Publicado: (2023)

Identification of hub genes and transcription factor-miRNA-mRNA pathways in mice and human renal ischemia-reperfusion injury
por: Ke, Peng, et al.
Publicado: (2021)

Transcriptional profiling to identify the key genes and pathways of pterygium
por: Chen, Yihui, et al.
Publicado: (2020)

Screening of potential key ferroptosis-related genes in sepsis
por: Cui, Shunan, et al.
Publicado: (2022)

Identification of key candidate genes and biological pathways in bladder cancer
por: Gao, Xin, et al.
Publicado: (2018)

In silico analyses for potential key genes associated with gastric cancer
por: Yan, Ping, et al.
Publicado: (2018)

Bioinformatics analysis of key genes and pathways in Hashimoto thyroiditis tissues
por: Zheng, Long, et al.
Publicado: (2020)

Key genes and co-expression modules involved in asthma pathogenesis
por: Huang, Yuyi, et al.
Publicado: (2020)

Identification of key gene modules and genes in colorectal cancer by co-expression analysis weighted gene co-expression network analysis
por: Wang, Peng, et al.
Publicado: (2020)

Identification of key genes and pathways associated with cholangiocarcinoma development based on weighted gene correlation network analysis
por: Liu, Jingwei, et al.
Publicado: (2019)

Identification of hub genes associated with the pathogenesis of diffuse large B-cell lymphoma subtype one characterized by host response via integrated bioinformatic analyses
por: Zhou, Lingna, et al.
Publicado: (2020)

Bioinformatic analysis of key pathways and genes involved in pediatric atopic dermatitis
por: Wang, Tianyi, et al.
Publicado: (2021)

Identification of key genes in bovine muscle development by co-expression analysis
por: Zhang, Junxing, et al.
Publicado: (2023)

Identification and validation of key genes associated with pathogenesis and prognosis of gastric cancer
por: Li, Ai, et al.
Publicado: (2023)

Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments
por: Lei, Xiaohua, et al.
Publicado: (2021)

Computational analysis of functional SNPs in Alzheimer’s disease-associated endocytosis genes
por: Tey, Han Jieh, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vmktdog4jncgt5nt2qpadnnmaq