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Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
The primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud’s phenomenon. In northern Sweden, a nested case–control study was performed on subjects reporting Raynaud’s phenomenon (N=461), and controls (N=763) matched by age, sex and geograp...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381957/ https://www.ncbi.nlm.nih.gov/pubmed/34415235 http://dx.doi.org/10.1080/22423982.2021.1969745 |
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author | Stjernbrandt, Albin Abu Mdaighem, Mahmoud Pettersson, Hans |
author_facet | Stjernbrandt, Albin Abu Mdaighem, Mahmoud Pettersson, Hans |
author_sort | Stjernbrandt, Albin |
collection | PubMed |
description | The primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud’s phenomenon. In northern Sweden, a nested case–control study was performed on subjects reporting Raynaud’s phenomenon (N=461), and controls (N=763) matched by age, sex and geographical location. The response rate to the exposure questionnaire was 79.2%. The study showed no statistically significant association between occupational noise exposure and reporting Raynaud’s phenomenon (OR 1.10; 95% CI 0.83–1.46) in simple analyses. However, there was a trend towards increasing OR for Raynaud’s phenomenon with increasing noise exposure, although not statistically significant. Also, there was a significant association between noise exposure and hearing loss (OR 2.76; 95% CI 2.00–3.81), and hearing loss was associated with reporting Raynaud’s phenomenon (OR 1.52; 95% CI 1.03–2.23) in a multiple regression model. In conclusion, self-reported occupational noise exposure was not statistically significantly associated with Raynaud’s phenomenon, but there was a dose–effect trend. In addition, the multiple model showed a robust association between hearing loss and Raynaud’s phenomenon. These findings offer some support for a common pathophysiological background for Raynaud’s phenomenon and hearing loss among noise-exposed workers, possibly through noise-induced vasoconstriction. |
format | Online Article Text |
id | pubmed-8381957 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-83819572021-08-24 Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study Stjernbrandt, Albin Abu Mdaighem, Mahmoud Pettersson, Hans Int J Circumpolar Health Original Research Article The primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud’s phenomenon. In northern Sweden, a nested case–control study was performed on subjects reporting Raynaud’s phenomenon (N=461), and controls (N=763) matched by age, sex and geographical location. The response rate to the exposure questionnaire was 79.2%. The study showed no statistically significant association between occupational noise exposure and reporting Raynaud’s phenomenon (OR 1.10; 95% CI 0.83–1.46) in simple analyses. However, there was a trend towards increasing OR for Raynaud’s phenomenon with increasing noise exposure, although not statistically significant. Also, there was a significant association between noise exposure and hearing loss (OR 2.76; 95% CI 2.00–3.81), and hearing loss was associated with reporting Raynaud’s phenomenon (OR 1.52; 95% CI 1.03–2.23) in a multiple regression model. In conclusion, self-reported occupational noise exposure was not statistically significantly associated with Raynaud’s phenomenon, but there was a dose–effect trend. In addition, the multiple model showed a robust association between hearing loss and Raynaud’s phenomenon. These findings offer some support for a common pathophysiological background for Raynaud’s phenomenon and hearing loss among noise-exposed workers, possibly through noise-induced vasoconstriction. Taylor & Francis 2021-08-20 /pmc/articles/PMC8381957/ /pubmed/34415235 http://dx.doi.org/10.1080/22423982.2021.1969745 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Article Stjernbrandt, Albin Abu Mdaighem, Mahmoud Pettersson, Hans Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study |
title | Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study |
title_full | Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study |
title_fullStr | Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study |
title_full_unstemmed | Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study |
title_short | Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study |
title_sort | occupational noise exposure and raynaud’s phenomenon: a nested case–control study |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381957/ https://www.ncbi.nlm.nih.gov/pubmed/34415235 http://dx.doi.org/10.1080/22423982.2021.1969745 |
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