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Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study

The primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud’s phenomenon. In northern Sweden, a nested case–control study was performed on subjects reporting Raynaud’s phenomenon (N=461), and controls (N=763) matched by age, sex and geograp...

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Autores principales: Stjernbrandt, Albin, Abu Mdaighem, Mahmoud, Pettersson, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381957/
https://www.ncbi.nlm.nih.gov/pubmed/34415235
http://dx.doi.org/10.1080/22423982.2021.1969745
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author Stjernbrandt, Albin
Abu Mdaighem, Mahmoud
Pettersson, Hans
author_facet Stjernbrandt, Albin
Abu Mdaighem, Mahmoud
Pettersson, Hans
author_sort Stjernbrandt, Albin
collection PubMed
description The primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud’s phenomenon. In northern Sweden, a nested case–control study was performed on subjects reporting Raynaud’s phenomenon (N=461), and controls (N=763) matched by age, sex and geographical location. The response rate to the exposure questionnaire was 79.2%. The study showed no statistically significant association between occupational noise exposure and reporting Raynaud’s phenomenon (OR 1.10; 95% CI 0.83–1.46) in simple analyses. However, there was a trend towards increasing OR for Raynaud’s phenomenon with increasing noise exposure, although not statistically significant. Also, there was a significant association between noise exposure and hearing loss (OR 2.76; 95% CI 2.00–3.81), and hearing loss was associated with reporting Raynaud’s phenomenon (OR 1.52; 95% CI 1.03–2.23) in a multiple regression model. In conclusion, self-reported occupational noise exposure was not statistically significantly associated with Raynaud’s phenomenon, but there was a dose–effect trend. In addition, the multiple model showed a robust association between hearing loss and Raynaud’s phenomenon. These findings offer some support for a common pathophysiological background for Raynaud’s phenomenon and hearing loss among noise-exposed workers, possibly through noise-induced vasoconstriction.
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spelling pubmed-83819572021-08-24 Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study Stjernbrandt, Albin Abu Mdaighem, Mahmoud Pettersson, Hans Int J Circumpolar Health Original Research Article The primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud’s phenomenon. In northern Sweden, a nested case–control study was performed on subjects reporting Raynaud’s phenomenon (N=461), and controls (N=763) matched by age, sex and geographical location. The response rate to the exposure questionnaire was 79.2%. The study showed no statistically significant association between occupational noise exposure and reporting Raynaud’s phenomenon (OR 1.10; 95% CI 0.83–1.46) in simple analyses. However, there was a trend towards increasing OR for Raynaud’s phenomenon with increasing noise exposure, although not statistically significant. Also, there was a significant association between noise exposure and hearing loss (OR 2.76; 95% CI 2.00–3.81), and hearing loss was associated with reporting Raynaud’s phenomenon (OR 1.52; 95% CI 1.03–2.23) in a multiple regression model. In conclusion, self-reported occupational noise exposure was not statistically significantly associated with Raynaud’s phenomenon, but there was a dose–effect trend. In addition, the multiple model showed a robust association between hearing loss and Raynaud’s phenomenon. These findings offer some support for a common pathophysiological background for Raynaud’s phenomenon and hearing loss among noise-exposed workers, possibly through noise-induced vasoconstriction. Taylor & Francis 2021-08-20 /pmc/articles/PMC8381957/ /pubmed/34415235 http://dx.doi.org/10.1080/22423982.2021.1969745 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research Article
Stjernbrandt, Albin
Abu Mdaighem, Mahmoud
Pettersson, Hans
Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
title Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
title_full Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
title_fullStr Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
title_full_unstemmed Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
title_short Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
title_sort occupational noise exposure and raynaud’s phenomenon: a nested case–control study
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381957/
https://www.ncbi.nlm.nih.gov/pubmed/34415235
http://dx.doi.org/10.1080/22423982.2021.1969745
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