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Crystal structure and Hirshfeld surface analysis of ethyl 6′-amino-2′-(chloro­meth­yl)-5′-cyano-2-oxo-1,2-di­hydro­spiro­[indoline-3,4′-pyran]-3′-carboxyl­ate

The mol­ecular conformation of the title compound, C(17)H(14)ClN(3)O(4), is stabilized by an intra­molecular C—H⋯O contact, forming an S(6) ring motif. In the crystal, the mol­ecules are connected by N—H⋯O hydrogen-bond pairs along the b-axis direction as dimers with R (2) (2)(8) and R (2) (2)(14) r...

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Detalles Bibliográficos
Autores principales: Naghiyev, Farid N., Grishina, Maria M., Khrustalev, Victor N., Akkurt, Mehmet, Huseynova, Afet T., Akobirshoeva, Anzurat A., Mamedov, İbrahim G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382051/
https://www.ncbi.nlm.nih.gov/pubmed/34513022
http://dx.doi.org/10.1107/S2056989021006459
Descripción
Sumario:The mol­ecular conformation of the title compound, C(17)H(14)ClN(3)O(4), is stabilized by an intra­molecular C—H⋯O contact, forming an S(6) ring motif. In the crystal, the mol­ecules are connected by N—H⋯O hydrogen-bond pairs along the b-axis direction as dimers with R (2) (2)(8) and R (2) (2)(14) ring motifs and as ribbons formed by inter­molecular C—H⋯N hydrogen bonds. There are weak van der Waals inter­actions between the ribbons. The most important contributions to the surface contacts are from H⋯H (34.9%), O⋯H/H⋯O (19.2%), C⋯H/H⋯C (11.9%), Cl⋯H/H⋯Cl (10.7%) and N⋯H/H⋯N (10.4%) inter­actions, as concluded from a Hirshfeld surface analysis.