Advances in Purification of SARS-CoV-2 Spike Ectodomain Protein Using High-Throughput Screening and Non-Affinity Methods

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The spike (S) glycoprotein of the pandemic virus, SARS-CoV-2, is a critically important target of vaccine design and therapeutic development. A high-yield, scalable, cGMP-compliant downstream process for the stabilized, soluble, native-like S protein ectodomain is necessary to meet the extensive mat...

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Detalles Bibliográficos
Autores principales: Cibelli, Nicole L., Arias, Gabriel F., Figur, McKenzie L., Khayat, Shireen S., Leach, Kristin M., Loukinov, Ivan, Gulla, Krishana C., Gowetski, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382130/
https://www.ncbi.nlm.nih.gov/pubmed/34426807
http://dx.doi.org/10.21203/rs.3.rs-778537/v1
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