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Extreme value theory as a framework for understanding mutation frequency distribution in cancer genomes
Currently, the population dynamics of preclonal cancer cells before clonal expansion of tumors has not been sufficiently addressed thus far. By focusing on preclonal cancer cell population as a Darwinian evolutionary system, we formulated and analyzed the observed mutation frequency among tumors (MF...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382180/ https://www.ncbi.nlm.nih.gov/pubmed/34424899 http://dx.doi.org/10.1371/journal.pone.0243595 |