Structure–Activity Relationship of Fluorinated Sialic Acid Inhibitors for Bacterial Sialylation

[Image: see text] Bacterial pathogens such as Nontypeable Haemophilus influenzae (NTHi) can evade the immune system by taking up and presenting host-derived sialic acids. Herein, we report a detailed structure–activity relationship of sialic acid-based inhibitors that prevent the transfer of host si...

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Detalles Bibliográficos
Autores principales: Moons, Sam J., Rossing, Emiel, Heming, Jurriaan J. A., Janssen, Mathilde A. C. H., van Scherpenzeel, Monique, Lefeber, Dirk J., de Jonge, Marien I., Langereis, Jeroen D., Boltje, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382218/
https://www.ncbi.nlm.nih.gov/pubmed/34043338
http://dx.doi.org/10.1021/acs.bioconjchem.1c00194

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