Cargando…

Nanoparticles for Directed Immunomodulation: Mannose-Functionalized Glycodendrimers Induce Interleukin-8 in Myeloid Cell Lines

[Image: see text] New therapeutic strategies for personalized medicine need to involve innovative pharmaceutical tools, for example, modular nanoparticles designed for direct immunomodulatory properties. We synthesized mannose-functionalized poly(propyleneimine) glycodendrimers with a novel architec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jatczak-Pawlik, Izabela, Gorzkiewicz, Michał, Studzian, Maciej, Zinke, Robin, Appelhans, Dietmar, Klajnert-Maculewicz, Barbara, Pułaski, Łukasz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382243/ https://www.ncbi.nlm.nih.gov/pubmed/34286584 http://dx.doi.org/10.1021/acs.biomac.1c00476

Ejemplares similares

Sugar-Modified Poly(propylene imine) Dendrimers Stimulate the NF-κB Pathway in a Myeloid Cell Line
por: Jatczak-Pawlik, Izabela, et al.
Publicado: (2016)

Mesalazine–PAMAM Nanoparticles for Transporter-Independent Intracellular Drug Delivery: Cellular Uptake and Anti-Inflammatory Activity
por: Gorzkiewicz, Michal, et al.
Publicado: (2023)

Synthesis, Internalization and Visualization of N-(4-Carbomethoxy) Pyrrolidone Terminated PAMAM [G5:G3-TREN] Tecto(dendrimers) in Mammalian Cells †
por: Studzian, Maciej, et al.
Publicado: (2020)

DOTA Glycodendrimers as Cu(II) Complexing Agents and Their Dynamic Interaction Characteristics toward Liposomes
por: Carone, Marianna, et al.
Publicado: (2020)

Sugar Modification Enhances Cytotoxic Activity of PAMAM-Doxorubicin Conjugate in Glucose-Deprived MCF-7 Cells – Possible Role of GLUT1 Transporter
por: Sztandera, Krzysztof, et al.
Publicado: (2019)

Poly(lysine) Dendrimers Form Complexes with siRNA and Provide Its Efficient Uptake by Myeloid Cells: Model Studies for Therapeutic Nucleic Acid Delivery
por: Gorzkiewicz, Michał, et al.
Publicado: (2020)

TLR2 activation induces antioxidant defence in human monocyte-macrophage cell line models
por: Karwaciak, Iwona, et al.
Publicado: (2017)

Calcium Dyshomeostasis Alters CCL5 Signaling in Differentiated PC12 Cells
por: Radzik, Tomasz, et al.
Publicado: (2019)

Glycodendrimers: tools to explore multivalent galectin-1 interactions
por: Cousin, Jonathan M, et al.
Publicado: (2015)

Heterovalent Glycodendrimers as Epitope Carriers for Antitumor Synthetic Vaccines
por: Pifferi, Carlo, et al.
Publicado: (2017)

Identification of Nanomolar Lectin Ligands by a Glycodendrimer Microarray
por: Laigre, Eugénie, et al.
Publicado: (2018)

Design, Synthetic Strategies, and Therapeutic Applications of Heterofunctional Glycodendrimers
por: Mousavifar, Leila, et al.
Publicado: (2021)

In Search of a Phosphorus Dendrimer-Based Carrier of Rose Bengal: Tyramine Linker Limits Fluorescent and Phototoxic Properties of a Photosensitizer
por: Sztandera, Krzysztof, et al.
Publicado: (2020)

Glutamate Deregulation in Ketamine-Induced Psychosis—A Potential Role of PSD95, NMDA Receptor and PMCA Interaction
por: Lisek, Malwina, et al.
Publicado: (2017)

Syntheses of Sulfo-Glycodendrimers Using Click Chemistry and Their Biological Evaluation
por: Miura, Yoshiko, et al.
Publicado: (2012)

Metabolic labelling of cancer cells with glycodendrimers stimulate immune-mediated cytotoxicity
por: Goyard, David, et al.
Publicado: (2021)

COVID-19 and cardiovascular complications – preliminary results of the LATE-COVID study
por: Lewek, Joanna, et al.
Publicado: (2021)

Glycodendrimers and Modified ELISAs: Tools to Elucidate Multivalent Interactions of Galectins 1 and 3
por: Wolfenden, Mark, et al.
Publicado: (2015)

Triazine–Carbosilane Dendrimersomes Enhance Cellular Uptake and Phototoxic Activity of Rose Bengal in Basal Cell Skin Carcinoma Cells
por: Sztandera, Krzysztof, et al.
Publicado: (2022)

Noncovalent Interactions with PAMAM and PPI Dendrimers Promote the Cellular Uptake and Photodynamic Activity of Rose Bengal: The Role of the Dendrimer Structure
por: Sztandera, Krzysztof, et al.
Publicado: (2021)

Bola‐Amphiphilic Glycodendrimers: New Carbohydrate‐Mimicking Scaffolds to Target Carbohydrate‐Binding Proteins
por: Zhang, Wenzheng, et al.
Publicado: (2022)

Silver Nanoparticles Surface-Modified with Carbosilane Dendrons as Carriers of Anticancer siRNA
por: Pędziwiatr-Werbicka, Elżbieta, et al.
Publicado: (2020)

Intrinsic Fluorescence of PAMAM Dendrimers—Quenching Studies
por: Konopka, Malgorzata, et al.
Publicado: (2018)

Synthesis and Nuclear Magnetic Resonance Structural Evaluation of Oxime-Linked Oligosialic Acid-Based Glycodendrimers
por: Cerney, James P., et al.
Publicado: (2023)

Conjugate of PAMAM Dendrimer, Doxorubicin and Monoclonal Antibody—Trastuzumab: The New Approach of a Well-Known Strategy
por: Marcinkowska, Monika, et al.
Publicado: (2018)

Multicomponent Conjugates of Anticancer Drugs and Monoclonal Antibody with PAMAM Dendrimers to Increase Efficacy of HER-2 Positive Breast Cancer Therapy
por: Marcinkowska, Monika, et al.
Publicado: (2019)

Nanovesicles displaying functional linear and branched oligomannose self-assembled from sequence-defined Janus glycodendrimers
por: Xiao, Qi, et al.
Publicado: (2020)

Central Nervous System and Peripheral Expression of CCL19, CCL21 and Their Receptor CCR7 in Experimental Model of Multiple Sclerosis
por: Bielecki, Bartosz, et al.
Publicado: (2015)

Biochemical and cardiovascular predictors of PIMS-TS risk in children after COVID-19 recovery: preliminary results of the LATE-COVID-Kids Study
por: Jatczak-Pawlik, Izabela, et al.
Publicado: (2022)

Immunomodulators: interleukins, interferons, and IV immunoglobulin
por: Roelofs, Joris J., et al.
Publicado: (2008)

CCR6 blockade on regulatory T cells ameliorates experimental model of multiple sclerosis
por: JATCZAK-PAWLIK, IZABELA, et al.
Publicado: (2020)

Molecular Mechanisms of Antitumor Activity of PAMAM Dendrimer Conjugates with Anticancer Drugs and a Monoclonal Antibody
por: Marcinkowska, Monika, et al.
Publicado: (2019)

Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults
por: Sokołowska, Anna, et al.
Publicado: (2020)

D-Mannose Enhanced Immunomodulation of Periodontal Ligament Stem Cells via Inhibiting IL-6 Secretion
por: Guo, Lijia, et al.
Publicado: (2018)

Cytotoxicity of Dendrimers
por: Janaszewska, Anna, et al.
Publicado: (2019)

In Vitro Studies of Polyhedral Oligo Silsesquioxanes: Evidence for Their Low Cytotoxicity
por: Janaszewska, Anna, et al.
Publicado: (2015)

Screening the Expression of ABCB6 in Erythrocytes Reveals an Unexpectedly High Frequency of Lan Mutations in Healthy Individuals
por: Koszarska, Magdalena, et al.
Publicado: (2014)

Unusual Enhancement of Doxorubicin Activity on Co-Delivery with Polyhedral Oligomeric Silsesquioxane (POSS)
por: Sobierajska, Ewelina, et al.
Publicado: (2017)

Fighting autoinflammation in FIRES: The role of interleukins and early immunomodulation
por: Perulli, Marco, et al.
Publicado: (2022)

Star-Shaped Poly(furfuryl glycidyl ether)-Block-Poly(glyceryl glycerol ether) as an Efficient Agent for the Enhancement of Nifuratel Solubility and for the Formation of Injectable and Self-Healable Hydrogel Platforms for the Gynaecological Therapies
por: Ziemczonek, Piotr, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_92ni7k0lnlvgaflvcqfksccg4d