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EnHiC: learning fine-resolution Hi-C contact maps using a generative adversarial framework

MOTIVATION: The high-throughput chromosome conformation capture (Hi-C) technique has enabled genome-wide mapping of chromatin interactions. However, high-resolution Hi-C data requires costly, deep sequencing; therefore, it has only been achieved for a limited number of cell types. Machine learning m...

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Detalles Bibliográficos
Autores principales: Hu, Yangyang, Ma, Wenxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382278/
https://www.ncbi.nlm.nih.gov/pubmed/34252966
http://dx.doi.org/10.1093/bioinformatics/btab272