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EnHiC: learning fine-resolution Hi-C contact maps using a generative adversarial framework
MOTIVATION: The high-throughput chromosome conformation capture (Hi-C) technique has enabled genome-wide mapping of chromatin interactions. However, high-resolution Hi-C data requires costly, deep sequencing; therefore, it has only been achieved for a limited number of cell types. Machine learning m...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382278/ https://www.ncbi.nlm.nih.gov/pubmed/34252966 http://dx.doi.org/10.1093/bioinformatics/btab272 |