Cargando…

Fucoidan-Supplemented Diet Potentiates Immune Checkpoint Blockage by Enhancing Antitumor Immunity

Immune checkpoint blockade (ICB) therapies such as PD-1 antibodies have produced significant clinical responses in treating a variety of human malignancies, yet only a subset of cancer patients benefit from such therapy. To improve the ICB efficacy, combinations with additional therapeutics were und...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Juan, Yang, Xianzhi, Pan, Wenfeng, Wang, Mingshuo, Lu, Yuxiong, Zhang, Jianeng, Fang, Ziqian, Zhang, Xiaomin, Ji, Yin, Bei, Jin-Xin, Dong, Jiajun, Wu, Yi, Pan, Chaoyun, Yu, Guangli, Zhou, Penghui, Li, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382313/ https://www.ncbi.nlm.nih.gov/pubmed/34434936 http://dx.doi.org/10.3389/fcell.2021.733246

Ejemplares similares

Cannabis suppresses antitumor immunity by inhibiting JAK/STAT signaling in T cells through CNR2
por: Xiong, Xinxin, et al.
Publicado: (2022)

Immune checkpoint: The novel target for antitumor therapy
por: Jiang, Xianghu, et al.
Publicado: (2019)

MYCN mediates TFRC-dependent ferroptosis and reveals vulnerabilities in neuroblastoma
por: Lu, Yuxiong, et al.
Publicado: (2021)

Enhancement of Immune Checkpoint Inhibitor-Mediated Anti-Cancer Immunity by Intranasal Treatment of Ecklonia cava Fucoidan against Metastatic Lung Cancer
por: Zhang, Wei, et al.
Publicado: (2021)

Antitumor effect and molecular mechanism of fucoidan in NSCLC
por: Chen, Xiaohan, et al.
Publicado: (2021)

Fucoidan from Macrocystis pyrifera Has Powerful Immune-Modulatory Effects Compared to Three Other Fucoidans
por: Zhang, Wei, et al.
Publicado: (2015)

Atypical Skin Manifestations During Immune Checkpoint Blockage in Coronavirus Disease 2019–Infected Patients With Lung Cancer
por: Rolfo, Christian, et al.
Publicado: (2020)

Adaptive antitumor immune response stimulated by bio-nanoparticle based vaccine and checkpoint blockade
por: Bai, Xuewei, et al.
Publicado: (2022)

PTCH1 mutation promotes antitumor immunity and the response to immune checkpoint inhibitors in colorectal cancer patients
por: Wang, Yanni, et al.
Publicado: (2021)

Blockade of novel immune checkpoints and new therapeutic combinations to boost antitumor immunity
por: Archilla-Ortega, Adrià, et al.
Publicado: (2022)

S100A4 blockage alleviates agonistic anti-CD137 antibody-induced liver pathology without disruption of antitumor immunity
por: Zhang, Jinhua, et al.
Publicado: (2018)

ANK2 as a novel predictive biomarker for immune checkpoint inhibitors and its correlation with antitumor immunity in lung adenocarcinoma
por: Zhang, Wengang, et al.
Publicado: (2022)

Immune Checkpoint Inhibitors and Neurotoxicity
por: Zhao, Zhiyi, et al.
Publicado: (2021)

Pleiotropic Effects of Metformin on the Antitumor Efficiency of Immune Checkpoint Inhibitors
por: Liu, Wenhui, et al.
Publicado: (2021)

FcγRIIB is a T cell checkpoint in antitumor immunity
por: Farley, Clara R., et al.
Publicado: (2021)

Activating the Antitumor Immune Response in Non-Hodgkin Lymphoma Using Immune Checkpoint Inhibitors
por: Joshi, Maansi, et al.
Publicado: (2020)

Antitumor activity of fucoidan: a systematic review and meta-analysis
por: Cao, Ling-Min, et al.
Publicado: (2021)

Programmed Cell Death-Ligand-1 expression in Bladder Schistosomal Squamous Cell Carcinoma – There’s room for Immune Checkpoint Blockage?
por: Madureira, Ana C.
Publicado: (2022)

Identification and Validation of Immune Markers in Coronary Heart Disease
por: Pan, Yuxiong, et al.
Publicado: (2022)

Reporting of Immune Checkpoint Inhibitor Therapy–Associated Diabetes, 2015–2019
por: Liu, Jiaqing, et al.
Publicado: (2020)

Combination of immune checkpoint blockade and targeted gene regulation of angiogenesis for facilitating antitumor immunotherapy
por: Zhan, Jing, et al.
Publicado: (2023)

Integrated analysis of the relation to tumor immune microenvironment and predicted value of Stonin1 gene for immune checkpoint blockage and targeted treatment in kidney renal clear cell carcinoma
por: Zheng, Axiu, et al.
Publicado: (2023)

Research progress in immune checkpoint inhibitors for lung cancer in China
por: Gan, Jiadi, et al.
Publicado: (2021)

An Improved Device Clears Blockages in the Tube of Irrigation and Drainage Systems
por: Yang, Shaozheng, et al.
Publicado: (2021)

Gamma delta T-cell-based immune checkpoint therapy: attractive candidate for antitumor treatment
por: Gao, Zhifei, et al.
Publicado: (2023)

Abrine Elicits Liver Carcinoma Immunity and Enhances Antitumor Efficacy of Immune Checkpoint Blockade by Modulating PD-L1 Signaling
por: Zhang, Shaowu
Publicado: (2022)

In situ vaccination with cowpea mosaic virus elicits systemic antitumor immunity and potentiates immune checkpoint blockade
por: Mao, Chenkai, et al.
Publicado: (2022)

Photothermally sensitive gold nanocage augments the antitumor efficiency of immune checkpoint blockade in immune “cold” tumors
por: Xiao, Guixiu, et al.
Publicado: (2023)

Clec4A4 Acts as a Negative Immune Checkpoint Regulator to Suppress Antitumor Immunity
por: Uto, Tomofumi, et al.
Publicado: (2023)

Ongoing Phase I Studies of Immune Checkpoint Inhibitors in China
por: Fang, Wenfeng, et al.
Publicado: (2019)

PD-1 immune checkpoint blockade may be viable for the prevention and treatment of elderly patients with POCD [Letter]
por: Wei, Penghui, et al.
Publicado: (2019)

Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer
por: Zhu, Shaoming, et al.
Publicado: (2021)

Adrenergic Signaling: A Targetable Checkpoint Limiting Development of the Antitumor Immune Response
por: Qiao, Guanxi, et al.
Publicado: (2018)

The Antitumor Activity of Combinations of Cytotoxic Chemotherapy and Immune Checkpoint Inhibitors Is Model-Dependent
por: Grasselly, Chloé, et al.
Publicado: (2018)

TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity
por: Bi, Jiacheng, et al.
Publicado: (2021)

Immune-related pneumonitis associated with immune checkpoint inhibitors in lung cancer: a network meta-analysis
por: Chen, Xinru, et al.
Publicado: (2020)

Blockage of EGFR/AKT and mevalonate pathways synergize the antitumor effect of temozolomide by reprogramming energy metabolism in glioblastoma
por: Cui, Xiaoteng, et al.
Publicado: (2023)

Predictive biomarkers for tumor immune checkpoint blockade
por: Tong, Mengting, et al.
Publicado: (2018)

In vitro Antitumor Properties of Fucoidan-Coated, Doxorubicin-Loaded, Mesoporous Polydopamine Nanoparticles
por: Xu, Hongping, et al.
Publicado: (2022)

PD-1 blockage combined with vaccine therapy can facilitate immune infiltration in tumor microenvironment of Lynch syndrome colon cancer
por: Ye, Kai, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bftb7gdolvvu0hedd2dop153e9