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Hypoxic-Ischemic Encephalopathy-Induced Seizure in an 11-Year-Old Female

Hypoxic-ischemic encephalopathy (HIE) typically manifests in the neonatal period. The degree of hypoxia following intrapartum asphyxia determines the structural changes in the brain, which can cause functional deficits in the affected child leading to developmental deficits and recurrent seizures. M...

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Detalles Bibliográficos
Autores principales: Pandav, Krunal, Ishak, Angela, Chohan, Farah, Edaki, Omoyeme, Quinonez, Jonathan, Ruxmohan, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382482/
https://www.ncbi.nlm.nih.gov/pubmed/34447644
http://dx.doi.org/10.7759/cureus.16606
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author Pandav, Krunal
Ishak, Angela
Chohan, Farah
Edaki, Omoyeme
Quinonez, Jonathan
Ruxmohan, Samir
author_facet Pandav, Krunal
Ishak, Angela
Chohan, Farah
Edaki, Omoyeme
Quinonez, Jonathan
Ruxmohan, Samir
author_sort Pandav, Krunal
collection PubMed
description Hypoxic-ischemic encephalopathy (HIE) typically manifests in the neonatal period. The degree of hypoxia following intrapartum asphyxia determines the structural changes in the brain, which can cause functional deficits in the affected child leading to developmental deficits and recurrent seizures. Management requires physical therapy, occupational therapy, and anti-seizure medications. We present a rare case of an 11-year-old female with a past medical history of epilepsy and cerebral atrophy secondary to hypoxic injury at birth. The patient presented to the hospital following a witnessed seizure and loss of consciousness for one hour. Given the past medical history and clinical findings, it was determined that a mild-to-moderate encephalopathic process resulted in a lower seizure threshold. HIE can manifest beyond the neonate years mainly due to the structural changes within the brain. Therefore, it is essential to understand aspects of HIE beyond the neonate years to manage this condition for a better patient outcome.
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spelling pubmed-83824822021-08-25 Hypoxic-Ischemic Encephalopathy-Induced Seizure in an 11-Year-Old Female Pandav, Krunal Ishak, Angela Chohan, Farah Edaki, Omoyeme Quinonez, Jonathan Ruxmohan, Samir Cureus Neurology Hypoxic-ischemic encephalopathy (HIE) typically manifests in the neonatal period. The degree of hypoxia following intrapartum asphyxia determines the structural changes in the brain, which can cause functional deficits in the affected child leading to developmental deficits and recurrent seizures. Management requires physical therapy, occupational therapy, and anti-seizure medications. We present a rare case of an 11-year-old female with a past medical history of epilepsy and cerebral atrophy secondary to hypoxic injury at birth. The patient presented to the hospital following a witnessed seizure and loss of consciousness for one hour. Given the past medical history and clinical findings, it was determined that a mild-to-moderate encephalopathic process resulted in a lower seizure threshold. HIE can manifest beyond the neonate years mainly due to the structural changes within the brain. Therefore, it is essential to understand aspects of HIE beyond the neonate years to manage this condition for a better patient outcome. Cureus 2021-07-24 /pmc/articles/PMC8382482/ /pubmed/34447644 http://dx.doi.org/10.7759/cureus.16606 Text en Copyright © 2021, Pandav et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Pandav, Krunal
Ishak, Angela
Chohan, Farah
Edaki, Omoyeme
Quinonez, Jonathan
Ruxmohan, Samir
Hypoxic-Ischemic Encephalopathy-Induced Seizure in an 11-Year-Old Female
title Hypoxic-Ischemic Encephalopathy-Induced Seizure in an 11-Year-Old Female
title_full Hypoxic-Ischemic Encephalopathy-Induced Seizure in an 11-Year-Old Female
title_fullStr Hypoxic-Ischemic Encephalopathy-Induced Seizure in an 11-Year-Old Female
title_full_unstemmed Hypoxic-Ischemic Encephalopathy-Induced Seizure in an 11-Year-Old Female
title_short Hypoxic-Ischemic Encephalopathy-Induced Seizure in an 11-Year-Old Female
title_sort hypoxic-ischemic encephalopathy-induced seizure in an 11-year-old female
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382482/
https://www.ncbi.nlm.nih.gov/pubmed/34447644
http://dx.doi.org/10.7759/cureus.16606
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