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Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes

AIMS/HYPOTHESIS: Increased levels of branched-chain amino acids (BCAAs) are associated with type 2 diabetes pathogenesis. However, most metabolomic studies are limited to an analysis of plasma metabolites under fasting conditions, rather than the dynamic shift in response to a metabolic challenge. M...

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Detalles Bibliográficos
Autores principales:	Sjögren, Rasmus J. O., Rizo-Roca, David, Chibalin, Alexander V., Chorell, Elin, Furrer, Regula, Katayama, Shintaro, Harada, Jun, Karlsson, Håkan K. R., Handschin, Christoph, Moritz, Thomas, Krook, Anna, Näslund, Erik, Zierath, Juleen R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382616/ https://www.ncbi.nlm.nih.gov/pubmed/34131782 http://dx.doi.org/10.1007/s00125-021-05481-9

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