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Linearized esculentin-2EM shows pH dependent antibacterial activity with an alkaline optimum

Here the hypothesis that linearized esculentin 2EM (E2EM-lin) from Glandirana emeljanovi possesses pH dependent activity is investigated. The peptide showed weak activity against Gram-negative bacteria (MLCs ≥ 75.0 μM) but potent efficacy towards Gram-positive bacteria (MLCs ≤ 6.25 μM). E2EM-lin ado...

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Detalles Bibliográficos
Autores principales:	Malik, Erum, Phoenix, David A., Snape, Timothy J., Harris, Frederick, Singh, Jaipaul, Morton, Leslie H. G., Dennison, Sarah R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382640/ https://www.ncbi.nlm.nih.gov/pubmed/34091807 http://dx.doi.org/10.1007/s11010-021-04181-7

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