Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control

AIMS/HYPOTHESIS: Type 2 diabetes increases the risk of cardiovascular and renal complications, but early risk prediction could lead to timely intervention and better outcomes. Genetic information can be used to enable early detection of risk. METHODS: We developed a multi-polygenic risk score (multi...

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Detalles Bibliográficos
Autores principales: Tremblay, Johanne, Haloui, Mounsif, Attaoua, Redha, Tahir, Ramzan, Hishmih, Camil, Harvey, François, Marois-Blanchet, François-Christophe, Long, Carole, Simon, Paul, Santucci, Lara, Hizel, Candan, Chalmers, John, Marre, Michel, Harrap, Stephen, Cífková, Renata, Krajčoviechová, Alena, Matthews, David R., Williams, Bryan, Poulter, Neil, Zoungas, Sophia, Colagiuri, Stephen, Mancia, Giuseppe, Grobbee, Diederick E., Rodgers, Anthony, Liu, Liusheng, Agbessi, Mawussé, Bruat, Vanessa, Favé, Marie-Julie, Harwood, Michelle P., Awadalla, Philip, Woodward, Mark, Hussin, Julie G., Hamet, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382653/
https://www.ncbi.nlm.nih.gov/pubmed/34226943
http://dx.doi.org/10.1007/s00125-021-05491-7

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