Tetrathiomolybdate (TM)-associated copper depletion influences collagen remodeling and immune response in the pre-metastatic niche of breast cancer

Tetrathiomolybdate (TM) is a novel, copper-depleting compound associated with promising survival in a phase II study of patients with high-risk and triple-negative breast cancer. We sought to elucidate the mechanism of TM by exploring its effects on collagen processing and immune function in the tum...

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Detalles Bibliográficos
Autores principales: Liu, Ying L., Bager, Cecilie Liv, Willumsen, Nicholas, Ramchandani, Divya, Kornhauser, Naomi, Ling, Lu, Cobham, Marta, Andreopoulou, Eleni, Cigler, Tessa, Moore, Anne, LaPolla, Dayle, Fitzpatrick, Veronica, Ward, Maureen, Warren, J. David, Fischbach, Claudia, Mittal, Vivek, Vahdat, Linda T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382701/
https://www.ncbi.nlm.nih.gov/pubmed/34426581
http://dx.doi.org/10.1038/s41523-021-00313-w

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