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Retinoic Acid Induces Functionally Suppressive Foxp3(+)RORγt(+) T Cells In Vitro

INTRODUCTION: CD4(+) T cells with regulatory function co-expressing Foxp3 and RORγt are linked to the development of oral tolerance towards innocuous food antigens in mice. This study aimed to discern the role played by IL-6 and retinoic acid (RA) in the in vitro generation of Foxp3(+)RORγt(+) T cel...

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Detalles Bibliográficos
Autores principales: Martínez-Blanco, Mónica, Lozano-Ojalvo, Daniel, Pérez-Rodríguez, Leticia, Benedé, Sara, Molina, Elena, López-Fandiño, Rosina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382797/
https://www.ncbi.nlm.nih.gov/pubmed/34447371
http://dx.doi.org/10.3389/fimmu.2021.675733

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