Cargando…

AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions

AMPA receptor (AMPAR) abundance and positioning at excitatory synapses regulates the strength of transmission. Changes in AMPAR localisation can enact synaptic plasticity, allowing long-term information storage, and is therefore tightly controlled. Multiple mechanisms regulating AMPAR synaptic ancho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watson, Jake F., Pinggera, Alexandra, Ho, Hinze, Greger, Ingo H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382838/ https://www.ncbi.nlm.nih.gov/pubmed/34426577 http://dx.doi.org/10.1038/s41467-021-25281-4

Ejemplares similares

Characterizing the binding and function of TARP γ8-selective AMPA receptor modulators
por: Dohrke, Jan-Niklas, et al.
Publicado: (2020)

Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics
por: Zhang, Danyang, et al.
Publicado: (2023)

Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain
por: Watson, Jake F, et al.
Publicado: (2017)

Mechanisms underlying TARP modulation of the GluA1/2-γ8 AMPA receptor
por: Herguedas, Beatriz, et al.
Publicado: (2022)

Mechanism of modulation of AMPA receptors by TARP-γ8
por: Carrillo, Elisa, et al.
Publicado: (2019)

Mapping the Interaction Sites between AMPA Receptors and TARPs Reveals a Role for the Receptor N-Terminal Domain in Channel Gating
por: Cais, Ondrej, et al.
Publicado: (2014)

SNP rs10420324 in the AMPA receptor auxiliary subunit TARP γ-8 regulates the susceptibility to antisocial personality disorder
por: Peng, Shi-Xiao, et al.
Publicado: (2021)

Comparative Dynamics of NMDA- and AMPA-Glutamate Receptor N-Terminal Domains
por: Dutta, Anindita, et al.
Publicado: (2012)

Dual Effects of TARP γ-2 on Glutamate Efficacy Can Account for AMPA Receptor Autoinactivation
por: Coombs, Ian D., et al.
Publicado: (2017)

TARPγ2 Is Required for Normal AMPA Receptor Expression and Function in Direction-Selective Circuits of the Mammalian Retina
por: Stincic, Todd, et al.
Publicado: (2023)

AMPA receptor trafficking and LTP: Carboxy-termini, amino-termini and TARPs
por: Díaz-Alonso, Javier, et al.
Publicado: (2021)

TARP γ-2 Is Required for Inflammation-Associated AMPA Receptor Plasticity within Lamina II of the Spinal Cord Dorsal Horn
por: Sullivan, Steve J., et al.
Publicado: (2017)

Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway
por: Sakai, Yusuke, et al.
Publicado: (2021)

Activity-Mediated AMPA Receptor Remodeling, Driven by Alternative Splicing in the Ligand-Binding Domain
por: Penn, Andrew C., et al.
Publicado: (2012)

Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor
por: Zhang, Danyang, et al.
Publicado: (2023)

The Conserved Tarp Actin Binding Domain Is Important for Chlamydial Invasion
por: Jewett, Travis J., et al.
Publicado: (2010)

AMPA Receptor Function in Hypothalamic Synapses
por: Royo, Maria, et al.
Publicado: (2022)

TARP γ-7 selectively enhances synaptic expression of calcium-permeable AMPARs
por: Studniarczyk, Dorota, et al.
Publicado: (2013)

Allosteric coupling of sub-millisecond clamshell motions in ionotropic glutamate receptor ligand-binding domains
por: Rajab, Suhaila, et al.
Publicado: (2021)

TARP as antigen in cancer immunotherapy
por: Vanhooren, Jolien, et al.
Publicado: (2021)

An inhalation anaesthesia approach for neonatal mice allowing streamlined stereotactic injection in the brain
por: Ho, Hinze, et al.
Publicado: (2020)

AMPA receptors in the synapse turnover by monomer diffusion
por: Morise, Jyoji, et al.
Publicado: (2019)

PDZ binding of TARP©-8 controls synaptic transmission, but not synaptic plasticity
por: Sumioka, Akio, et al.
Publicado: (2011)

Analysis of high-affinity assembly for AMPA receptor amino-terminal domains
por: Zhao, Huaying, et al.
Publicado: (2012)

Analysis of high-affinity assembly for AMPA receptor amino-terminal domains
por: Zhao, Huaying, et al.
Publicado: (2013)

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains
por: Zhao, Huaying, et al.
Publicado: (2017)

Molecular characterization of the feline T-cell receptor γ alternate reading frame protein (TARP) ortholog
por: Weiss, Alexander Th. A., et al.
Publicado: (2012)

Structure, Dynamics, and Allosteric Potential of Ionotropic Glutamate Receptor N-Terminal Domains
por: Krieger, James, et al.
Publicado: (2015)

Analytical modelling of temperature effects on an AMPA-type synapse
por: Kufel, Dominik S., et al.
Publicado: (2018)

Enhanced TARP-γ8-PSD-95 coupling in excitatory neurons contributes to the rapid antidepressant-like action of ketamine in male mice
por: Xue, Shi-Ge, et al.
Publicado: (2023)

Phosphorylation of the AMPAR-TARP Complex in Synaptic Plasticity
por: Park, Joongkyu
Publicado: (2018)

Synapse Type-Dependent Expression of Calcium-Permeable AMPA Receptors
por: Lalanne, Txomin, et al.
Publicado: (2018)

Mechanistic Understanding of the Phosphorylation-Induced Conformational Rigidity at the AMPA Receptor C-terminal Domain
por: Chatterjee, Sudeshna, et al.
Publicado: (2019)

In vivo evidence for the involvement of the carboxy terminal domain in assembling connexin 36 at the electrical synapse
por: Helbig, Ingo, et al.
Publicado: (2010)

Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing
por: Penn, Andrew C., et al.
Publicado: (2013)

AMPAR/TARP stoichiometry differentially modulates channel properties
por: Miguez-Cabello, Federico, et al.
Publicado: (2020)

GluA2-lacking AMPA receptors in hippocampal CA1 cell synapses: evidence from gene-targeted mice
por: Rozov, Andrei, et al.
Publicado: (2012)

Acute Inactivation of PSD-95 Destabilizes AMPA Receptors at Hippocampal Synapses
por: Yudowski, Guillermo A., et al.
Publicado: (2013)

Input-specific homeostatic regulation of AMPA receptor accumulation at central synapses
por: Hou, Qingming, et al.
Publicado: (2012)

A Mechanistic Model of NMDA and AMPA Receptor-Mediated Synaptic Transmission in Individual Hippocampal CA3-CA1 Synapses: A Computational Multiscale Approach
por: Micheli, Pietro, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0gju6gopan4kv08u1798q8uvdj