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Protective effects of metformin against myocardial ischemia-reperfusion injury via AMPK-dependent suppression of NOX4
Numerous studies have demonstrated that metformin can reduce the incidence of myocardial infarction and improve the prognosis of patients. However, its specific mechanism has not been determined. Using a rat model of myocardial ischemia-reperfusion injury (MIRI), it was observed that metformin signi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383039/ https://www.ncbi.nlm.nih.gov/pubmed/34396450 http://dx.doi.org/10.3892/mmr.2021.12351 |