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Protective effects of metformin against myocardial ischemia-reperfusion injury via AMPK-dependent suppression of NOX4

Numerous studies have demonstrated that metformin can reduce the incidence of myocardial infarction and improve the prognosis of patients. However, its specific mechanism has not been determined. Using a rat model of myocardial ischemia-reperfusion injury (MIRI), it was observed that metformin signi...

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Detalles Bibliográficos
Autores principales:	Shi, Yan, Hou, Shu-Ai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383039/ https://www.ncbi.nlm.nih.gov/pubmed/34396450 http://dx.doi.org/10.3892/mmr.2021.12351

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