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Reactive oxygen species induced by uric acid promote NRK-52E cell apoptosis through the NEK7-NLRP3 signaling pathway

Increasing uric acid (UA) could induce renal tubular epithelial cell (NRK-52E) injury. However, the specific mechanism by which UA induces renal tubular epithelial cell injury remains unknown. It was hypothesized that UA induces renal tubular epithelial cell injury through reactive oxygen species (R...

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Detalles Bibliográficos
Autores principales:	Li, Dongdong, Wang, Luobing, Ou, Jiaoying, Wang, Chuanxu, Zhou, Jiabao, Lu, Lili, Wu, Yanshneg, Gao, Jiandong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383041/ https://www.ncbi.nlm.nih.gov/pubmed/34414459 http://dx.doi.org/10.3892/mmr.2021.12368

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