The G132S Mutation Enhances the Resistance of Mycobacterium tuberculosis β-Lactamase against Sulbactam

[Image: see text] The current rise of antibiotic resistant forms of Mycobacterium tuberculosis is a global health threat that calls for new antibiotics. The β-lactamase BlaC of this pathogen prevents the use of β-lactam antibiotics, except in combination with a β-lactamase inhibitor. To understand i...

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Detalles Bibliográficos
Autores principales: van Alen, Ilona, Chikunova, Aleksandra, Safeer, Adil A., Ahmad, Misbha Ud Din, Perrakis, Anastassis, Ubbink, Marcellus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383266/
https://www.ncbi.nlm.nih.gov/pubmed/34250791
http://dx.doi.org/10.1021/acs.biochem.1c00168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383266/
https://www.ncbi.nlm.nih.gov/pubmed/34250791
http://dx.doi.org/10.1021/acs.biochem.1c00168

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