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Semisynthetic Macrocyclic Lipo-lanthipeptides Display Antimicrobial Activity Against Bacterial Pathogens

[Image: see text] A large number of antimicrobial peptides depend on intramolecular disulfide bonds for their biological activity. However, the relative instability of disulfide bonds has limited the potential of some of these peptides to be developed into therapeutics. Conversely, peptides containi...

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Detalles Bibliográficos
Autores principales: Zhao, Xinghong, Xu, Yanli, Viel, Jakob H., Kuipers, Oscar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383303/
https://www.ncbi.nlm.nih.gov/pubmed/34347446
http://dx.doi.org/10.1021/acssynbio.1c00161