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deepMNN: Deep Learning-Based Single-Cell RNA Sequencing Data Batch Correction Using Mutual Nearest Neighbors

It is well recognized that batch effect in single-cell RNA sequencing (scRNA-seq) data remains a big challenge when integrating different datasets. Here, we proposed deepMNN, a novel deep learning-based method to correct batch effect in scRNA-seq data. We first searched mutual nearest neighbor (MNN)...

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Detalles Bibliográficos
Autores principales: Zou, Bin, Zhang, Tongda, Zhou, Ruilong, Jiang, Xiaosen, Yang, Huanming, Jin, Xin, Bai, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383340/
https://www.ncbi.nlm.nih.gov/pubmed/34447413
http://dx.doi.org/10.3389/fgene.2021.708981

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