Upregulation of leukocyte immunoglobulin-like receptor B4 on interstitial macrophages in COPD; their possible protective role against emphysema formation

BACKGROUND: Leukocyte immunoglobulin-like receptor B4 (LILRB4) is one of the inhibitory receptors in various types of immune cells including macrophages. Previous reports suggested that LILRB4 could be involved in a negative feedback system to prevent excessive inflammatory responses. However, its r...

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Detalles Bibliográficos
Autores principales: Mitsune, Ayumi, Yamada, Mitsuhiro, Fujino, Naoya, Numakura, Tadahisa, Ichikawa, Tomohiro, Suzuki, Ayumi, Matsumoto, Shuichiro, Mitsuhashi, Yoshiya, Itakura, Koji, Makiguchi, Tomonori, Koarai, Akira, Tamada, Tsutomu, Endo, Shota, Takai, Toshiyuki, Okada, Yoshinori, Suzuki, Satoshi, Ichinose, Masakazu, Sugiura, Hisatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383377/
https://www.ncbi.nlm.nih.gov/pubmed/34425800
http://dx.doi.org/10.1186/s12931-021-01828-3

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