Inhibition of P2X4R attenuates white matter injury in mice after intracerebral hemorrhage by regulating microglial phenotypes

BACKGROUND: White matter injury (WMI) is a major neuropathological event associated with intracerebral hemorrhage (ICH). P2X purinoreceptor 4 (P2X4R) is a member of the P2X purine receptor family, which plays a crucial role in regulating WMI and neuroinflammation in central nervous system (CNS) dise...

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Detalles Bibliográficos
Autores principales: Fu, Xiongjie, Zhou, Guoyang, Wu, Xinyan, Xu, Chaoran, Zhou, Hang, Zhuang, Jianfeng, Peng, Yucong, Cao, Yang, Zeng, Hanhai, Li, Yin, Li, Jianru, Gao, Liansheng, Chen, Gao, Wang, Lin, Yan, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383380/
https://www.ncbi.nlm.nih.gov/pubmed/34425835
http://dx.doi.org/10.1186/s12974-021-02239-3

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