Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse brain

BACKGROUND: Genetic variants in the voltage-gated sodium channels SCN1A, SCN2A, SCN3A, and SCN8A are leading causes of epilepsy, developmental delay, and autism spectrum disorder. The mRNA splicing patterns of all four genes vary across development in the rodent brain, including mutually exclusive c...

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Detalles Bibliográficos
Autores principales: Liang, Lindsay, Fazel Darbandi, Siavash, Pochareddy, Sirisha, Gulden, Forrest O., Gilson, Michael C., Sheppard, Brooke K., Sahagun, Atehsa, An, Joon-Yong, Werling, Donna M., Rubenstein, John L. R., Sestan, Nenad, Bender, Kevin J., Sanders, Stephan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383430/
https://www.ncbi.nlm.nih.gov/pubmed/34425903
http://dx.doi.org/10.1186/s13073-021-00949-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383430/
https://www.ncbi.nlm.nih.gov/pubmed/34425903
http://dx.doi.org/10.1186/s13073-021-00949-0

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