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Blockage of bacterial FimH prevents mucosal inflammation associated with Crohn’s disease

BACKGROUND: An Escherichia coli (E. coli) pathotype with invasive properties, first reported by Darfeuille-Michaud and termed adherent-invasive E. coli (AIEC), was shown to be prevalent in up to half the individuals with Crohn’s Disease (CD), suggesting that these bacteria could be involved in the p...

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Detalles Bibliográficos
Autores principales: Chevalier, Grégoire, Laveissière, Arnaud, Desachy, Guillaume, Barnich, Nicolas, Sivignon, Adeline, Maresca, Marc, Nicoletti, Cendrine, Di Pasquale, Eric, Martinez-Medina, Margarita, Simpson, Kenneth William, Yajnik, Vijay, Sokol, Harry, Plassais, Jonathan, Strozzi, Francesco, Cervino, Alessandra, Morra, Rachel, Bonny, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383459/
https://www.ncbi.nlm.nih.gov/pubmed/34425887
http://dx.doi.org/10.1186/s40168-021-01135-5