IgG Immune Complexes Inhibit Naïve T Cell Proliferation and Suppress Effector Function in Cytotoxic T Cells

Elevated levels of circulating immune complexes are associated with autoimmunity and with worse prognoses in cancer. Here, we examined the effects of well-defined, soluble immune complexes (ICs) on human peripheral T cells. We demonstrate that IgG-ICs inhibit the proliferation and differentiation of...

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Detalles Bibliográficos
Autores principales: Charab, Wissam, Rosenberger, Matthew G., Shivram, Haridha, Mirazee, Justin M., Donkor, Moses, Shekhar, Soumya R., Gjuka, Donjeta, Khoo, Kimberly H., Kim, Jin Eyun, Iyer, Vishwanath R., Georgiou, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383740/
https://www.ncbi.nlm.nih.gov/pubmed/34447380
http://dx.doi.org/10.3389/fimmu.2021.713704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383740/
https://www.ncbi.nlm.nih.gov/pubmed/34447380
http://dx.doi.org/10.3389/fimmu.2021.713704

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