Cargando…

IgG Immune Complexes Inhibit Naïve T Cell Proliferation and Suppress Effector Function in Cytotoxic T Cells

Elevated levels of circulating immune complexes are associated with autoimmunity and with worse prognoses in cancer. Here, we examined the effects of well-defined, soluble immune complexes (ICs) on human peripheral T cells. We demonstrate that IgG-ICs inhibit the proliferation and differentiation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Charab, Wissam, Rosenberger, Matthew G., Shivram, Haridha, Mirazee, Justin M., Donkor, Moses, Shekhar, Soumya R., Gjuka, Donjeta, Khoo, Kimberly H., Kim, Jin Eyun, Iyer, Vishwanath R., Georgiou, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383740/ https://www.ncbi.nlm.nih.gov/pubmed/34447380 http://dx.doi.org/10.3389/fimmu.2021.713704

Ejemplares similares

Identification and removal of sequencing artifacts produced by mispriming during reverse transcription in multiple RNA-seq technologies
por: Shivram, Haridha, et al.
Publicado: (2018)

Chd1 co-localizes with early transcription elongation factors independently of H3K36 methylation and releases stalled RNA polymerase II at introns
por: Park, Daechan, et al.
Publicado: (2014)

MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network
por: Shivram, Haridha, et al.
Publicado: (2019)

PRC2 activates interferon-stimulated genes indirectly by repressing miRNAs in glioblastoma
por: Shivram, Haridha, et al.
Publicado: (2019)

An Engineered Human Fc variant With Exquisite Selectivity for FcγRIIIa(V158) Reveals That Ligation of FcγRIIIa Mediates Potent Antibody Dependent Cellular Phagocytosis With GM-CSF-Differentiated Macrophages
por: Kang, Tae Hyun, et al.
Publicado: (2019)

CD70 CAR T cells in AML: Form follows function
por: Mirazee, Justin, et al.
Publicado: (2022)

Migratory Properties of Naive, Effector, and Memory Cd8(+) T Cells
por: Weninger, Wolfgang, et al.
Publicado: (2001)

Diverse ATPase Proteins in Mobilomes Constitute a Large Potential Sink for Prokaryotic Host ATP
por: Shim, Hyunjin, et al.
Publicado: (2021)

Decreased Numbers of CD4(+) Naive and Effector Memory T Cells, and CD8(+) Naïve T Cells, are Associated with Trichloroethylene Exposure
por: Hosgood, H. Dean, et al.
Publicado: (2012)

miRNA Profiling of Naïve, Effector and Memory CD8 T Cells
por: Wu, Haoquan, et al.
Publicado: (2007)

Tumor masses support naive T cell infiltration, activation, and differentiation into effectors
por: Thompson, Elizabeth D., et al.
Publicado: (2010)

Fatty acids in non-alcoholic steatohepatitis: Focus on pentadecanoic acid
por: Yoo, Wonbeak, et al.
Publicado: (2017)

The Ligands for Human IgG and Their Effector Functions
por: de Taeye, Steven W., et al.
Publicado: (2019)

Lineage Tracking the Generation of T Regulatory Cells From Microbial Activated T Effector Cells in Naïve Mice
por: Zhu, Kun, et al.
Publicado: (2020)

Circulating naïve and effector memory T cells correlate with prognosis in head and neck squamous cell carcinoma
por: Takahashi, Hideyuki, et al.
Publicado: (2021)

Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
por: Watters, Kyle E., et al.
Publicado: (2020)

Atypical Human Effector/Memory CD4(+) T Cells With a Naive-Like Phenotype
por: Caccamo, Nadia, et al.
Publicado: (2018)

Impact of Glycosylation on Effector Functions of Therapeutic IgG †
por: Abès, Riad, et al.
Publicado: (2010)

CXCR3 Identifies Human Naive CD8(+) T Cells with Enhanced Effector Differentiation Potential
por: De Simone, Gabriele, et al.
Publicado: (2019)

Transcriptomic and proteomic assessment of tocilizumab response in a randomized controlled trial of patients hospitalized with COVID-19
por: Shivram, Haridha, et al.
Publicado: (2023)

Differential susceptibility of naïve, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission
por: Groot, Fedde, et al.
Publicado: (2006)

IgG Subclasses and Allotypes: From Structure to Effector Functions
por: Vidarsson, Gestur, et al.
Publicado: (2014)

IgG Fc engineering to modulate antibody effector functions
por: Wang, Xinhua, et al.
Publicado: (2017)

Cytokine-driven Proliferation and Differentiation of Human Naive, Central Memory, and Effector Memory CD4(+) T Cells
por: Geginat, Jens, et al.
Publicado: (2001)

Swift Development of Protective Effector Functions in Naive Cd8(+) T Cells against Malaria Liver Stages
por: Sano, Gen-ichiro, et al.
Publicado: (2001)

Developmental Stage, Phenotype, and Migration Distinguish Naive- and Effector/Memory-like CD4(+) Regulatory T Cells
por: Huehn, Jochen, et al.
Publicado: (2004)

Effect of human bone marrow mesenchymal stromal cells on cytokine production by peripheral blood naive, memory, and effector T cells
por: Laranjeira, Paula, et al.
Publicado: (2015)

VIPER regulates naive T cell activation and effector responses: Implication in TLR4 associated acute stage T cell responses
por: Sahoo, Subhransu Sekhar, et al.
Publicado: (2018)

Distinct migratory pattern of naive and effector T cells through the blood–CSF barrier following Echovirus 30 infection
por: Wiatr, Marie, et al.
Publicado: (2019)

Transfer of in vitro-expanded naïve T cells after lymphodepletion enhances antitumor immunity through the induction of polyclonal antitumor effector T cells
por: Tanaka, Tomohiro, et al.
Publicado: (2017)

Human interleukin 10 induces naive surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3
Publicado: (1994)

IgG3 collaborates with IgG1 and IgA to recruit effector function in RV144 vaccinees
por: Fischinger, Stephanie, et al.
Publicado: (2020)

CD40-Activated B Cells Can Efficiently Prime Antigen-Specific Naïve CD8(+) T Cells to Generate Effector but Not Memory T cells
por: Mathieu, Mélissa, et al.
Publicado: (2012)

PD-L1 is expressed on human activated naive effector CD4(+) T cells. Regulation by dendritic cells and regulatory CD4(+) T cells
por: Mazerolles, Fabienne, et al.
Publicado: (2021)

Reference Genes for Expression Studies in Human CD8(+) Naïve and Effector Memory T Cells under Resting and Activating Conditions
por: Geigges, Marco, et al.
Publicado: (2020)

Prognostic value of severe acute respiratory syndrome coronavirus‐2 viral load and antibodies in patients hospitalized with COVID‐19
por: Bauer, Rebecca N., et al.
Publicado: (2023)

Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants
por: Dashivets, Tetyana, et al.
Publicado: (2015)

Highly individual patterns of virus-immune IgG effector responses in humans
por: Corrales-Aguilar, Eugenia, et al.
Publicado: (2016)

Role of Fc Core Fucosylation in the Effector Function of IgG1 Antibodies
por: Golay, Josée, et al.
Publicado: (2022)

A Protein Antagonist of Activation-Induced Cytidine Deaminase Encoded by a Complex Mouse Retrovirus
por: Singh, Gurvani B., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_tb0adh3auuldg54dip5smqr2kq