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The designed NF-κB inhibitor, DHMEQ, inhibits KISS1R-mediated invasion and increases drug-sensitivity in mouse plasmacytoma SP2/0 cells

Plasmacytoma is one of the most difficult types of leukemia to treat, and it often invades the bone down to the marrow resulting in the development of multiple myeloma. NF-κB is often constitutively activated, and promotes metastasis and drug resistance in neoplastic cells. The present study assesse...

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Detalles Bibliográficos
Autores principales: Lin, Yinzhi, Sidthipong, Kulrawee, Ma, Jun, Koide, Naoki, Umezawa, Kazuo, Kubota, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383752/
https://www.ncbi.nlm.nih.gov/pubmed/34504546
http://dx.doi.org/10.3892/etm.2021.10526