CD4(+) T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope

Löfgren’s syndrome (LS) is an acute form of sarcoidosis characterized by a genetic association with HLA-DRB1*03 (HLA-DR3) and an accumulation of CD4(+) T cells of unknown specificity in the bronchoalveolar lavage (BAL). Here, we screened related LS-specific TCRs for antigen specificity and identifie...

Descripción completa

Detalles Bibliográficos
Autores principales: Greaves, Sarah A., Ravindran, Avinash, Santos, Radleigh G., Chen, Lan, Falta, Michael T., Wang, Yang, Mitchell, Angela M., Atif, Shaikh M., Mack, Douglas G., Tinega, Alex N., Maier, Lisa A., Dai, Shaodong, Pinilla, Clemencia, Grunewald, Johan, Fontenot, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383815/
https://www.ncbi.nlm.nih.gov/pubmed/34410304
http://dx.doi.org/10.1084/jem.20210785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383815/
https://www.ncbi.nlm.nih.gov/pubmed/34410304
http://dx.doi.org/10.1084/jem.20210785

Ejemplares similares