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Enhancer Pleiotropy, Gene Expression, and the Architecture of Human Enhancer–Gene Interactions
Enhancers are often studied as noncoding regulatory elements that modulate the precise spatiotemporal expression of genes in a highly tissue-specific manner. This paradigm has been challenged by recent evidence of individual enhancers acting in multiple tissues or developmental contexts. However, th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383896/ https://www.ncbi.nlm.nih.gov/pubmed/33749795 http://dx.doi.org/10.1093/molbev/msab085 |