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Transcriptional Profiling and Functional Analysis of N1/N2 Neutrophils Reveal an Immunomodulatory Effect of S100A9-Blockade on the Pro-Inflammatory N1 Subpopulation

Neutrophils have been classically viewed as a homogenous population. Recently, neutrophils were phenotypically classified into pro-inflammatory N1 and anti-inflammatory N2 sub-populations, but the functional differences between the two subtypes are not completely understood. We aimed to investigate...

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Detalles Bibliográficos
Autores principales: Mihaila, Andreea C., Ciortan, Letitia, Macarie, Razvan D., Vadana, Mihaela, Cecoltan, Sergiu, Preda, Mihai Bogdan, Hudita, Ariana, Gan, Ana-Maria, Jakobsson, Gabriel, Tucureanu, Monica M., Barbu, Elena, Balanescu, Serban, Simionescu, Maya, Schiopu, Alexandru, Butoi, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384118/
https://www.ncbi.nlm.nih.gov/pubmed/34447377
http://dx.doi.org/10.3389/fimmu.2021.708770